NEBNext^® Globin & rRNA Depletion Kit (Human/Mouse/Rat)

Globin mRNA and rRNA are highly abundant in blood samples, and their efficient and specific removal is desirable in order to reveal the biological significance of less abundant transcripts.

The NEBNext® Globin & rRNA Depletion Kit (Human/Mouse/Rat) employs the NEBNext RNase H-based RNA depletion workflow to deplete globin mRNA, cytoplasmic rRNA and mitochondrial rRNA with human, mouse and rat samples, and is effective with intact and degraded RNA.

• Efficient, specific depletion of rRNA and globin mRNA (adult, fetal and embryonic)
• Suitable for low-quality or high-quality RNA
• Compatible with a broad range of input amounts: 10 ng – 1 μg
• Optional integration with poly(A) mRNA isolation workflows for removal of globin RNAs, rRNAs, and noncoding RNAs
• Fast workflow: 2 hours, with less than 10 minutes hands-on time

The kit is also available with RNAClean^® beads.