Life Sensors是一家为药物发现和研究市场提供方法和建立可行性技术方法的生物技术公司。该公司为泛素和泛素蛋白酶体通路研究提供创新性的研究工具而占据世界。其原核和真核蛋白表达系统SUMOpro 和SUMOstar 已被世界范围内的学术、政府研究机构和制药、生物技术公司广泛应用。
LifeSensors, Inc., a biotechnology company that discovers and develops enabling technologies for therapeutic, drug discovery and research markets, has established its leadership position by providing innovative research tools for the ubiquitin and ubiquitin-like protein pathways. Its prokaryotic and eukaryotic protein expression platforms SUMOpro and SUMOstar are used worldwide by academic and government institutions, as well as pharmaceutical and biotechnology companies.
部分产品信息如下：
PRODUCTS
Expression Systems
Add your protein of interest to the growing bibliography of SUMO-expressed proteins!
Our SUMO-based expression system maximize the yield of soluble, functional proteins in E. coli, yeast, insect and mammalian cells. This system features SUMO functioning as both a chaperonin and as an initiator of protein folding to dramatically improve the solubility and level of expression of your protein of interest. Our desumoylases efficiently and precisely remove SUMO tags, releasing your protein with the desired N-terminal amino acid. Both the SUMO tags and the desumoylases have His6 tags making their subsequent removal fast and easy.
| Enhanced Expression and Solubility Using SUMO vs. Other Commonly-used Fusion Tags
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| Figure legend. GDF8 （myostatin）, a secreted TGFβ family member and difficult-to-express protein, was expressed in E. coli either as a His6, Ub, SUMO, MBP, GST, TRX, or NUS A fusion. Protein fractions were resolved by SDS-PAGE and stained with Coomassie. Arrowheads indicate expected/observed positions of respective protein bands. Of all tags tested, SUMO was the only fusion tag that provided high-level expression of soluble protein. |
Express your protein the first time and every time with SUMO. Choose your preferred expression system below and get started with SUMO today!