上海金畔生物科技有限公司提供Sulfo-MBS (进口，偶联剂) ，欢迎访问官网了解更多产品信息。
| 产品编号 | D-9003 |
| 英文名称 | Sulfo-MBS |
| 中文名称 | Sulfo-MBS (进口，偶联剂) |
| 别 名 | m-maleimidobenzoyl-N-hydroxysulfosuccinimide ester; 偶联剂; MBS; MMBS; N-(3-MALEIMIDOBENZOYLOXY)SUCCINAMIDE; N-(M-MALEIMIDOBENZOYLOXY)SUCCINAMIDE; N-(M-MALEIMIDOBENZOYLOXY)SUCCINIMIDE; NSC294786; M-MALEIMIDOBENZOICACIDN-HYDROXYSUCCINIMIDEESTER; M-MALEIMIDOBENZOYLN-HYDROXYSUCCINIMIDEESTER; M-MALEIMIDOBENZOYL-N-HYDROXYSUCCINIMIDE; |
| 保存条件 | Store at -20℃. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | MBS and its water-soluble analog Sulfo-MBS are heterobifunctional crosslinkers that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugation experiments involving these crosslinkers are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneously with the maleimide (sulfhydryl-targeted) reaction.
分子式：C15H9O9N2NaS 分子结构式： |
