牛胰岛素

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产品编号 P0005
英文名称 Bovine Insulin
中文名称 牛胰岛素
别    名 ILPR; INS; Insulin A chain; Insulin B chain; Insulin A chain; Insulin precursor; IRDN; Proinsulin; Proinsulin precursor; IDDM2; INS_BOVIN; MODY10; Bovine Insulin   
牛胰岛素
Specific References  (1)     |     P0005 has been referenced in 1 publications.
[IF=3.191] Wenjing Sun. et al. A homogeneous enzyme-free ratiometric immunoassay for the determination of C-peptide. ANAL BIOCHEM. 2022 Sep;:114899  Other ;  Other.  
PubMed:36126761

保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds.Belongs to the insulin family. The insulin-link growth factors, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, respectvely), share approximatly 76% sequence identity and are 50% related to pro-insulin.IGF-I and IGF-II are nonglycosylated, single chain proteins of 70 and 76 amino acids in length, respectivelly. IGF-I functions as an autocrine regulator of growth in vaious, whereas the function of IGF-II is less well defined.

SWISS:
P01317

Gene ID:
N/A

基本信息:

CAS:11070-73-8
分子式: C254H377N65O75S6
分子量: 5733.49
MDL: MFCD00131380
级别:BR
来源:牛胰腺
外观/性状:白色粉末
活性:≥27 USP units/mg
溶解性:0.01 M HCl: 5 mg/mL, 无色透明。

产品简介:

胰岛素(Insulin)是由胰脏内的胰岛β细胞受内源性或外源性物质如葡萄糖、乳糖、核糖、精氨酸、胰高血糖素等的刺激而分泌的一种蛋白质激素。胰岛素是机体内唯一降低血糖的激素,同时促进糖原、脂肪、蛋白质合成。外源性胰岛素主要用来治疗糖尿病。