pCMV-VSV-G载体序列


 pCMV-VSV-G载体序列说明书

型号 载体名称 出品公司 载体用途
VMA0369 pCMV-VSV-G Addgene 慢病毒载体
产品参数: 

5′ sequencing primer: T7

载体抗性: 
氨苄青霉素(Ampicillin)
载体描述: 

Vector for constitutive expression of VSV-G glycoprotein. Also known as pHCMV-G or pHCMV-VSV-G.

Retroviruses are efficient tools for delivering heritable genes into the genome of dividing cells. pCMV-VSV-G expresses the G glycoprotein of the vesicular stomatitis virus (VSV-G) under the control of the CMV immediate-early promoter. VSV-G is used in pseudotyping of Moloney Murine Leukenia Virus(MMLV)-based retroviral vectors by mediating viral entry. VSV-G interacts with phospholipidcomponents of the target cell membrane and fosters the fusion of viral and cellular membranes. VSV-G does not require a cell surface receptor and can serve as a surrogate viral envelope protein. 
The vector contains the ampicillin-resistance gene for propagation and antibiotic selection in bacteria.

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