产品编号

产品名称

规格

培养面积

容量

包装

MS-9035XZ

PrimeSurface^® 培养皿35mm

外寸35Φ×14(H)mm

9cm²

–

5包·50/case

MS-9060XZ

PrimeSurface^® 培养皿60mm

外寸60Φ×15(H)mm

21cm²

–

10包·100/case

MS-9090XZ

PrimeSurface^® 培养皿90mm

外寸90Φ×20(H)mm

57cm²

–

10包·50/case

MS-9024XZ

 Sumiron Celltight 板24F

24孔·平底

1.8cm² 

3.4mL/well

1包·10/case

产品编号

产品名称

孔数

孔底形状

容量

包装

MS-9384UZ

PrimeSurface^® 384U多孔板

384

U底

0.1mL

1/包・20/case

MS-9384WZ

PrimeSurface^® 384U白色多孔板

384

U底

0.1mL

1/包・20/case

MS-9096VZ

PrimeSurface^® 96V多孔板

96

V底

0.3mL

1/包・20/case

MS-9096MZ

PrimeSurface^® 96M多孔板

96

纺锤底

0.2mL

1/包・20/case

MS-9096UZ

PrimeSurface^® 96U多孔板

96

U底

0.3mL

1/包・20/case

MS-9096WZ

PrimeSurface^® 96U白色多孔板

96

U底

0.3mL

1/包・20/case

细胞块

3D打印后

拔出剑山后的三维结构体

细胞块

3D打印后（上面）

3D打印后（侧面）

拔出剑山后

没有细胞吸附在PrimeSurface® 96U多孔板上，也没有凌乱的细胞集落，已经形成均一。

一般市面上贩卖的漂浮培养用多孔板，细胞紧密粘附或者死亡。

研究领域

使用型号

参考文献

视网膜

研究

MS-9096V

KUWAHARA, Atsushi, et al. Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue. Nature communications, 2015, 6.: 1-15

MS-9096V

TANAKA, T., et al. Generation of retinal ganglion cells with functional axons from human induced pluripotent stem cells. Sci Rep, 2015, 5. 8344.

MS-9096U

EIRAKU, Mototsugu and SASAI, Yoshiki Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues. Nature protocols,

2012, 7. 1: 69-79. 

MS-9096V

NAKANO, Tokushige, et al. Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs. Cell Stem Cell, 2012, 10. 6: 771-785.

 MS-9096V

GAO, Lixiong, et al. Intermittent high oxygen influences the formation of neural retinal tissue from human embryonic stem cells.Scientific Reports, 2016, 6.

神经科学

研究

MS-9096V

MUGURUMA, Keiko, et al. Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells. Cell Reports, 2015, 10:537-550

MS-9096V

BAMBA, Y., et al. Differentiation, polarization, and migration of human induced pluripotent stem cell-derived neural progenitor cells co-cultured with a human glial cell   line with radial glial-like characteristics. Biochem Biophys Res Commun,   2014, 447. 4: 683-688. 

MS-9096 U, M or V

MINAMINO, Yuki, et al. Isolation and Propagation of Neural Crest Stem Cells from Mouse Embryonic Stem Cells via Cranial Neurospheres. Stem cells and development, 2014, 24.2:   172-181

MS-9096V

KADOSHIMA, T., et al. Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex. Proceedings of the National Academy of Sciences of the United States of   America, 2013, 110. 50: 20284-20289. 

MS-9096 U, M or V

OGAWA, Yasuhiro, et al. Impaired neural differentiation of induced pluripotent stem cells generated from a mouse model of Sandhoff disease. PLoS ONE, 2013, 8. 1: e55856.

MS-9035X

GOMI, Masanori, et al. Functional recovery of the murine brain ischemia model using human induced pluripotent stem cell-derived telencephalic progenitors. Brain research, 2012, 1459. 52-60. 

MS-9096 U, M or V

NASU, Makoto, et al. Robust formation and maintenance of continuous stratified cortical   neuroepithelium by laminin-containing matrix in mouse ES cell culture. PLoS ONE, 2012, 7. 12: e53024.

MS-9096 U

DANJO, T., et al. Subregional specification of embryonic stem cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals. The Journal of neuroscience : the official journal of the Society   for Neuroscience, 2011, 31. 5: 1919-1933.

MS-9096 U

KANEMURA, Yonehiro Development of cell-processing systems for human stem cells (neural stem cells, mesenchymal stem cells, and iPS cells) for regenerative medicine. The   Keio journal of medicine, 2010, 59. 2: 35-45.

MS-9096 U, M or V

MS-9035X, MS-9060X

or

MS-9090X

FUKUSUMI, Hayato, et al. (2016). Establishment of human neural progenitor cells from human induced pluripotent stem cells with diverse tissue. Stem cells international: 1-10.

 MS-9096 U, M or V

RAASCH, Martin, et al. (2016). An integrative microfluidically supported in vitro model of an endothelial barrier combined with cortical spheroids simulates effects of neuroinflammation in neocortex development. Biomicrofluidics. 10: 044102.

MS-9096 M

ISODA, Miho, et al. (2016). Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions. Neuroscienc   Research.

MS-9035X, MS-9060X

or

MS-9090X

BAMBA, Yohei, et al. (2016). In vitro characterization of neurite extension using induced pluripotent stem cells derived from lissencephaly patients with TUBA1A missense mutations. Molecular brain.

MS-9096V

SAKAGUCHI, Hideya, et al. (2015). Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue. Nature communications. 6: 1-11.

MS-9096V

MUGURUMA, Keiko, et al. Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells. Cell Reports, 2015, 10:537-550

KAMIYA, Daisuke, et al. Intrinsic transition of embryonic stem-cell differentiation into neural progenitors. Nature, 2011, 470. 7335: 503-509.

心肌细胞

研究和心脏研究

MS-9096V

TAKASHIMA, Yasuhiro, et al. Resetting transcription factor control circuitry toward ground-state pluripotency in human. Cell, 2014, 158. 6: 1254-1269.

MS-9035X

OTSUJI, Tomomi G, et al. Dynamic link between histone H3 acetylation and an increase in the functional characteristics of human ESC/iPSC-derived cardiomyocytes. PLoS ONE, 2012, 7. 9: e45010.

MS-9096U

SATOSHI, Yasuda, et al. AW551984: a novel regulator of cardiomyogenesis in pluripotent embryonic cells. Biochemical Journal, 2011, 437. 2: 345-355.

MS-9096U

YASUDA, S., et al. A novel regulator of cardiomyogenesis in pluripotent embryonic cells. The Biochemical journal, 2011, 437. 2: 345-355.

MS-9096U

OTSUJI, Tomomi G, et al. Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs. Stem cell research, 2010, 4. 3: 201-213.

MS-9035X, MS-9060X or MS-9090X

YAMAUCHI, Kaori, et al. Cardiomyocytes develop from anterior primitive streak cells induced by β‐catenin activation and the blockage of BMP signaling in hESCs. Genes to Cells, 2010, 15. 12: 1216-1227.

MS-9096V

GUO, Ge, et al. (2016). Naive pluripotent stem cells derived directly from isolated cells of the human innercell mass. Stem Cell Reports. 6: 437-446.

MS-9096 U

 MS-9035X, MS-9060X

or

MS-9090X

NOGUCHI, Ryo, et al. (2016). Development of a three-dimensional pre-vascularized scaffold-freecontractile cardiac patch for treating heart disease. The Journal of Heart and Lung Transplantation. 35: 137-145.

 MS-9096

NOGUCHI, Ryo, et al. Development of a Three-Dimensional Prevascularized Scaffold-Free Contractile Cardiac Patch for Treating Heart Disease. The Journal of Heart and Lung Transplantation, 2015,

肝细胞

研究

MS-9096 U, M or V

ISHII, Takamichi (2012).   Differentiation of Human Embryonic Stem Cells into Functional Hepatocyte-Like Cells (Method). Stem Cells and Cancer Stem Cells, Volume 2, Springer:   43-49. 

MS-9096 U, M or V

ISHII, Takamichi et al. (2012). Hepatic Maturation of hES Cells by Using a Murine Mesenchymal Cell Line Derived from Fetal Livers.Human Embryonic and Induced Pluripotent Stem Cells, Springer: 397-403.

MS-9096U

ISHII, Takamichi, et al. In vitro hepatic maturation of human embryonic stem cells by using a mesenchymal cell line derived from murine fetal livers. Cell and tissue research, 2010, 339. 3: 505-512. 

MS-9096U

YANAGIDA, Ayaka, et al. Liver maturation deficiency in p57 Kip2-/-mice occurs in a hepatocytic p57 Kip2 expression-independent manner. Developmental biology, 2015,

牙科

研究

MS-9035X, MS-9060X or MS-9090X

OZEKI, Nobuaki, et al. Differentiation of Human Skeletal Muscle Stem Cells into Odontoblasts Is Dependent on Induction of α1 Integrin Expression.Journal of Biological Chemistry, 2014, 289. 20: 14380-14391.

MS-9096 U, M or V

YAMAMOTO, Mioko, et al. Three-dimensional spheroid culture promotes odonto/osteoblastic differentiation of dental pulp cells.Archives of oral biology, 2014, 59. 3: 310-317.

生精小管

研究

MS-9096V

YOKONISHI, T., et al. In Vitro Reconstruction of Mouse Seminiferous Tubules Supporting Germ Cell Differentiation. Biol Reprod, 2013, 89. (1):15: 1–6.

iPS细胞

生成

MS-9035X

OHNISHI, Hiroe, et al. A comparative study of induced pluripotent stem cells generated from frozen, stocked bone marrow‐and adipose tissue‐derived mesenchymal stem cells. Journal of tissue engineering and regenerative medicine, 2012, 6. 4: 261-271. 1. 

MS-9035X

AOKI, T., et al. Generation of induced pluripotent stem cells from human adipose-derived stem cells without c-MYC. Tissue engineering. Part A, 2010, 16. 7: 2197-2206.

MS-9035X, MS-9060X or MS-9090X

ODA, Y., et al. Induction of pluripotent stem cells from human third molar mesenchymal stromal cells. J Biol Chem, 2010, 285. 38: 29270-29278.

OHNISHI, Hiroe, et al. Generation of Xeroderma Pigmentosum-A Patient-Derived Induced Pluripotent Stem Cell Line for Use As Future Disease Model. Cellular Reprogramming (Formerly" Cloning and Stem Cells"), 2015, 17. 4: 268-274.

EST（胚胎干细胞试验）

MS-9096W

SUZUKI, N., et al. Evaluation of novel high-throughput embryonic stem cell tests with new molecular markers for screening embryotoxic chemicals in vitro. Toxicological sciences : an official journal of the Society of Toxicology, 2011, 124. 2: 460-471.

MS-9096U

NAGAHORI, H., et al. (2016). Prediction of in vivo developmental toxicity by combination of Hand1-Luc embryonic stem cell test and metabolic stability test with clarification of metabolically inapplicable candidates. Toxicol Lett. 259: 44-51.

 MS-9096U

YU, Ruoxing, et al. (2015). A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early Embryogenesis. PLoS ONE. 10: e0145286.

MS-9096W

COZ, Florian Le, et al. (2015). Hand1-Luc Embryonic Stem Cell Test (Hand1-Luc EST): A novel rapid and highly reproducible in vitro test for embryotoxicity by measuring cytotoxicity and differentiation toxicity using engineered mouse ES cells. The Journal of Toxicological Sciences. 40: 251-261.

骨和软骨研究

MS-9096 U

HINO, Kyosuke, et al. (2015). Neofunction of ACVR1 in fibrodysplasia ossificans progressiva. Proceedings ofthe National Academy of Sciences. 112: 15438-15443.

MS-9096 U, M or V

MURATA, Daiki, et al. A preliminary study of osteochondral regeneration using a  scaffold-free threedimensional construct of porcine adipose tissue-derived mesenchymal stem cells. Journal of orthopaedic surgery and research, 2015, 10. 1: 1-12.

 MS-9096 U, M or V

FUJIMOTO, Mai, et al. Establishment of a novel model of chondrogenesis using murine embryonic stem cells carrying fibrodysplasia ossificans progressiva-associated mutant ALK2. Biochemical and Biophysical Research Communications,

2014, 455. 3: 347-352. 1.

MS-9096 U

ISHIHARA, Kohei, et al. Simultaneous regeneration of full-thickness cartilage and subchondral bone defects in vivo using a three-dimensional scaffold-free autologous construct derived from high-density bone marrow-derived mesenchymal stem cells. J Orthop Surg Res, 2014, 9. 1: 98. 1.

血管

研究

 MS-9096 U

MS-9035X, MS-9060X

or

MS-9090X

KAGEYAMA, Tatsuto, et al. (2016). In situ crosslinkable gelatin-CMC hydrogels designed for rapid engineering of perfusable vasculatures. ACS Biomaterials Science & Engineering.

MS-9096U

ITOH, M., et al. Scaffold-Free Tubular Tissues Created by a Bio-3D Printer Undergo Remodeling and Endothelialization when Implanted in Rat Aortae.PLoS ONE,

2015, 10. 9: e0136681.

胰岛细胞移植

MS-9096 U

NAKAMURA, Kentaro, et al. (2016). Introduction to a new cell transplantation platform via recombinant peptide petaloid pieces and its application to islet transplantation with mesenchymal stem cells. Transplant International. 29: 1039-1050.

骨髓

研究

 MS-9096 U

SAYO, Kanae, et al. (2016). Fabrication of bone marrow-like tissue in vitro from dispersed-state bone marrow cells. Regenerative Therapy. 3: 32-37.

其它

MS-9035X, MS-9060X

or

MS-9090X

ITO, Yoshitaka, et al. (2015). Establishment of Tsc2‑deficient rat embryonic stem cells. International journal of oncology. 46: 1944-1952.

 MS-9096 U, M or V

OGAWA, Yasuhiro, et al. (2015). Induced Pluripotent Stem Cells Generated from P0-Cre; Z/EG Transgenic Mice. PLoS ONE. 10: e0138620.

MS-9096U

IMAI, Hiroyuki, et al. Tetraploid Embryonic Stem Cells Maintain Pluripotency and Differentiation Potency into Three Germ Layers. PLoS ONE, 2015, 10. 6: e0130585.

MS-9096U, MS-9096M

or

MS-9096V

MITSUI, Kaoru, et al. Conditionally replicating adenovirus prevents pluripotent stem cell–derived teratoma by specifically eliminating undifferentiated cells. Molecular Therapy. Methods & Clinical Development, 2015, 2. 15026.

MS-9096U

ZHOU, Yuanshu, et al. Metabolic suppression during mesodermal differentiation of embryonic stem cells identified by single-cell comprehensive gene expression analysis. Molecular BioSystems, 2015, 11. 9: 2560-2567.

  1. 

ROTEM, Asaf, et al. Alternative to the soft-agar assay that permits high-throughput   drug and genetic screens for cellular transformation. Proceedings of the National Academy of Sciences, 2015, 1-6

  2.

OHNISHI, Ken, et al. Plastic induction of CD133AC133-positive cells in the microenvironment of glioblastoma spheroids.International Journal of Oncology, 2014, 45.2: 581-586.

  3.

KODAMA, Tatsushi, et al. A Novel Mechanism of EML4-ALK Rearrangement Mediated by Chromothripsis in a Patient-Derived Cell Line. Journal of Thoracic Oncology, 2014, 9.11: 1638-1646.

  4.

SHIMOZATO, O., et al. Receptor-type protein tyrosine phosphatase κ directly dephosphorylates CD133 and regulates downstream AKT activation. Oncogene, 2014.

  5.

MIKHAIL, Andrew S., et al. Image-based analysis of the size-and time-dependent penetration of polymeric micelles in multicellular tumor spheroids and tumor xenografts. International journal of pharmaceutics, 2014, 464.1: 168-177.

  6.

MORI, Masamichi, et al. The Selective Anaplastic Lymphoma Receptor Tyrosine Kinase Inhibitor ASP3026 Induces Tumor Regression and Prolongs Survival in Non–Small Cell Lung Cancer Model Mice. Molecular cancer therapeutics, 2014, 13.2: 329-340.

  7.

AKIMOTO, Miho, et al. An inhibitor of HIF-α subunit expression suppresses hypoxia-induced dedifferentiation of human NSCLC into cancer stem cell-like cells. World, 2013, 3.4: 41-45.

  8.

GOUDARZI, Houman, et al. Hypoxia affects in vitro growth of newly established cell lines from patients with malignant pleural mesothelioma. Biomedical Research, 2013, 34.1:   13-21.

  9.

KATO, Takuma; TANAKA, Masakazu; OBA, Makoto. Protein Transfection Study Using Multicellular Tumor Spheroids of Human Hepatoma Huh-7 Cells. PloS one, 2013, 8.12: e82876.

10.

MIKHAIL, Andrew S.; EETEZADI, Sina; ALLEN, Christine. Multicellular tumor spheroids for evaluation of cytotoxicity and tumor growth inhibitory effects of nanomedicines in vitro: A comparison of docetaxel-loaded block copolymer   micelles and Taxotere®.PloS one, 2013, 8.4: e62630.

11.

SATO, Shuji, et al. Identification of the cancer cell proliferation and survival functions of proHB-EGF by using an anti-HB-EGF antibody. PloS one, 2013, 8.1: e54509.

12.

ISHII, Genichiro, et al. Morphophenotype of floating colonies derived from a single cancer cell has a critical impact on tumor‐forming activity. Pathology international, 2013, 63.1: 29-36.

13.

OYANAGI, Jun, et al. Epithelial-mesenchymal transition stimulates human cancer cells   to extend microtubule-based invasive protrusions and suppresses cell growth in collagen gel. PloS one, 2012, 7.12: e53209.

14.

UNO,   Makiko, et al. Identification of physiologically active substances as novel ligands for MRGPRD. BioMed Research International, 2012, 2012.

15.

KONISHI, Hiroaki, et al. PEGylated liposome IHL-305 markedly improved the survival of ovarian cancer peritoneal metastasis in mouse. BMC cancer, 2012, 12.1: 462.

16.

NISHIMURA, Satoko, et al. MRGD, a MAS-related G-protein coupled receptor, promotes tumorigenisis and is highly expressed in lung cancer. PloS one, 2012, 7.6: e38618.

17.

SAKAMOTO, Hiroshi, et al. CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant. Cancer cell, 2011, 19.5: 679-690.

18.

KUNITA, Akiko, et al. Podoplanin is regulated by AP-1 and promotes platelet aggregation and cell migration in osteosarcoma. The American journal of pathology, 2011, 179.2: 1041-1049.

19.

SAKUMA, Yuji, et al. WZ4002, a third-generation EGFR inhibitor, can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more efficiently than Src inhibitors. Laboratory Investigation, 2011, 92.3: 371-383.

20.

SHIMIZU, Yutaka, et al. Dienogest, a synthetic progestin, inhibits prostaglandin E2 production and aromatase expression by human endometrial epithelial cells in a spheroid culture system. Steroids, 2011, 76.1: 60-67.

21.

KOSHIKAWA, Naohiko, et al. Proteolytic activation of heparin‐binding EGF‐like growth factor by membrane‐type matrix metalloproteinase‐1 in ovarian carcinoma cells. Cancer science, 2011, 102.1: 111-116.

22.

SAKAMOTO, Hiroshi, et al. CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant. Cancer cell, 2011, 19.5: 679-690.

23.

YAMAGUCHI,   Shigeru, et al. Novel Photodynamic Therapy Using Water‐dispersed TiO2–Polyethylene Glycol Compound: Evaluation of Antitumor Effect on Glioma Cells and Spheroids In Vitro. Photochemistry and photobiology,   2010, 86.4: 964-971.

24.

MATSUYAMA, Masahiro, et al. Reduced CD73 expression and its association with altered purine nucleotide metabolism in colorectal cancer cells robustly causing liver metastases. Oncology letters, 2010, 1.3: 431-436.

25.

KOGASHIWA, Yasunao, et al. Docetaxel suppresses invasiveness of head and neck cancer cells in vitro. Cancer science, 2010, 101.6: 1382-1386.

26.

HAN, Muri, et al. Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles. Molecular Therapy, 2009, 17.8: 1404-1410.

27.

WATANABE, Y., et al. A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy. Oncogene, 2009, 29.8: 1145-1154.

28.

KUNITA, Akiko, et al. The platelet aggregation-inducing factor aggrus/podoplanin promotes pulmonary metastasis. The American journal of pathology,   2007, 170.4: 1337-1347.

29.

HAN,  Muri, et al. Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies. Journal of Controlled Release, 2007, 121.1: 38-48.

30.

KESSEL, Sarah, et al. (2016). High-Throughput 3D Tumor Spheroid Screening Method for Cancer Drug Discovery Using Celigo Image Cytometry. Journal of laboratory automation: 2211068216652846.

31.

OZAWA, Masayuki (2015). The N-cadherin cytoplasmic domain confers anchorage-independent growth and the loss of contact inhibition. Scientific Reports. 5: 1-16.

32.

TARIQ, Mohammad, et al. (2016). Eukaryotic translation initiation factor 5A (eIF5A) is essential for HIF-1α activation in hypoxia. Biochemical and Biophysical Research Communications. 470: 417-424.

33.

TERASHIMA, Jun, et al. (2016). VEGF expression is regulated by HIF-1α and ARNT in 3D KYSE-70, esophageal cancer cell spheroids. Cell biology international.

34.

MASUDA, Mari, et al. (2016). TNIK inhibition abrogates colorectal cancer stemness. Nature communications. 7: 12586.

35.

SUDA, Yoshitaka, et al. (2016). Clonal heterogeneity in osteogenic potential of lung cancer-associated fibroblasts: promotional effect of osteogenic progenitor cells on cancer cell migration. Journal of cancer research and clinical oncology: 1-12.

36.

EETEZADI, Sina, et al. (2015). Effects of Doxorubicin Delivery Systems and Mild Hyperthermia on

Tissue Penetration in 3D Cell Culture Models of Ovarian Cancer Residual Disease. Molecular pharmaceutics. 12: 3973-3985.

37.

MISU, Masayasu, et al. Effects of Wnt-10b on proliferation and differentiation of murine melanoma cells.Biochemical and Biophysical Research Communications, 2015, 463. 4: 618-623.

38.

NAKANISHI, Yoshito, et al. Mechanism of oncogenic signal activation by the novel fusion kinase FGFR3– BAIAP2L1.Molecular cancer therapeutics, 2015, 14. 3: 704-712.

39.

NOZAWA-SUZUKI, Noriko, et al. The inhibitory effect of hypoxic cytotoxin on the expansion of cancer stem cells in ovarian cancer.Biochemical and Biophysical Research Communications, 2015, 457. 4: 706-711.

40.

YONESAKA, Kimio, et al. (2015). The pan-HER family tyrosine kinase inhibitor afatinib overcomes HER3 ligand heregulin-mediated resistance to EGFR inhibitors in non-small cell lung cancer. Oncotarget.    6: 33602.

41.

YONESAKA, K, et al. Anti-HER3 monoclonal antibody patritumab sensitizes refractory non-small cell lung cancer to the epidermal growth factor receptor inhibitor erlotinib.Oncogene, 2015

42.

YOSHIDA, Ryohei, et al. EGFR tyrosine kinase inhibitors combined with cytotoxic drugs for treatment of NSCLC with EGFR gene mutations: Efficacy and mechanisms.Cancer research, 2015, 75. 15 Supplement: 3501-3501.

43.

KODAMA, Tatsushi, et al. Alectinib shows potent antitumor activity against RET-rearranged non–small cell lung cancer.Molecular cancer therapeutics, 2014, 13. 12: 2910-2918.

44.

寺島潤 (2014). 肝がん 3D 細胞塊における薬物代謝酵素の不均一な発現. バイオテック 2014.

45.

中野洋文 難治性癌・癌肝細胞の三次元培養薬剤スクリーニング.Bio Garage, 2014, 22. 13.

46.

BRESLIN, Susan and O’DRISCOLL, Lorraine Three-dimensional cell culture: the missing link in drug discovery.Drug Discovery Today, 2013, 18. 5: 240-249.

47.

ISHII, Genichiro, et al. Morphophenotype of floating colonies derived from a single cancer cell has a critical impact on tumor-forming activity.Pathology International, 2013, 63. 1: 29-36.

48.

KATO, Takuma, et al. Protein Transfection Study Using Multicellular Tumor Spheroids of Human Hepatoma Huh-7 Cells.PLoS ONE, 2013, 8. 12: e82876.

49.

KESSEL, Sarah, et al. (2013). Progressing 3D Spheroid Analysis into a HTS Drug Discovery Method. Molecular biology of the cell, AMER SOC CELL BIOLOGY 8120 WOODMONT AVE, STE 750, BETHESDA, MD 20814-2755 USA.

50.

MASUDA, Taisuke, et al. A microfabricated platform to form three-dimensional toroidal multicellular aggregate.Biomedical microdevices, 2012, 14. 6: 1085-1093.

51.  

KOSHIKAWA, Naohiko, et al. Proteolytic activation of heparin-binding EGF-like growth factor by membrane-type matrix metalloproteinase-1 in ovarian carcinoma cells.Cancer science, 2011, 102. 1: 111-116.

1.

TAKASHIMA,   Yasuhiro, et al. Resetting transcription factor control circuitry toward   ground-state pluripotency in human. Cell, 2014, 158. 6: 1254-1269.   [MS-9096V]

2.

KIMURA,   Kenichi, et al. The Role of CCL5 in the Ability of Adipose Tissue-Derived   Mesenchymal Stem Cells to Support Repair of Ischemic Regions. Stem cells and development, 2013, 23. 5: 488-501. [MS-9096U]

3.

SHIMOTO,   Takeshi, et al. (2013). Bio Rapid Prototyping Project: Development of   Spheroid Formation System for Regenerative Medicine. Information Technology Convergence,   Springer: 855-862. [MS-9096 U, M or V]

4.

KOIDE,   Naoshi, et al. Establishment and optimal culture conditions of   microRNA-induced pluripotent stem cells generated from HEK293 cells via   transfection of microRNA-302s expression vector. Nagoya journal of medical science,   2012, 74. 1-2: 157-165. [MS-9096 U, M or V]

5.

MARKS, H., et al. The transcriptional and epigenomic foundations of ground state   pluripotency. Cell, 2012, 149. 3: 590-604. [MS-9096U]

6.

OHNISHI,   Hiroe, et al. (2012). Human Mesenchymal Stem Cells and iPS Cells (Preparation   Methods). Human Embryonic   and Induced Pluripotent Stem Cells, Springer:   173-190. [MS-9035X, MS-9060X or MS-9090X]

7.

SAKAI,   Yusuke, et al. Embryoid body culture of mouse embryonic stem cells using   microwell and micropatterned chips. Journal of bioscience and bioengineering, 2011, 111. 1: 85-91. [MS-9096U]

8.

TAKAYAMA,   Yuzo, et al. Toward the Precise Control of Cell Differentiation Processes by   Using Micro and Soft Lithography. 2011, [MS-9096 U, M or V]

9.

TAKAYAMA,   Yuzo, et al. Simultaneous induction of calcium transients in embryoid bodies   using microfabricated electrode substrates. Journal of bioscience and bioengineering, 2011, 112. 6: 624-629. [MS-9096U]

10.  

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K. Tsuji-Tamura, et al, Dual inhibition of mTORC1 and mTORC2 perturbs cytoskeletal organization andimpairs endothelial cell elongation. Biochemical and Biophysical Research Communications, 2018, 497.1.:326-331  [MS-9096U]

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E. C. Costa, et al, Spheroids Formation on Non‐Adhesive Surfaces by Liquid Overlay Technique: Considerations and Practical Approaches. Biotechnology Journal (Special Issue: Biotech Methods and Advances), 2018, 13.1 [MS-9096U

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R. Maruhashia, et el, Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research, 2018, 1865.3.:470-479 [MS-9096U]

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J. Terashima, The regulation mechanism of AhR activated by benzo[a]pyrene for CYP expression are different between 2D and 3D culture of human lung cancer cells. Drug Metabolism and Pharmacokinetics, 2018 [MS-9096V]

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F, Chisa Yoshimuraa, et el, Spontaneous hair follicle germ (HFG) formation in vitro, enabling the large-scale production of HFGs for regenerative medicine. Biomaterials, 2018, 154.: 291-30

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Michael Dunne, et el, Hyperthermia-mediated drug delivery induces biological effects at the tumor and molecular levels that improve cisplatin efficacy in triple negative breast cancer. Journal of Controlled Release, 2018, 282.28.: 35-45 [MS-9096]

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