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Exonuclease VII
- DNA specific exonuclease
- Cleaves linear single-stranded DNA in both the 3′ to 5′ and 5′ to 3′ directions
- Preferred substrate is linear single-stranded DNA
Exonuclease VII is ideal for:
- Removal of primers with or without 3′ or 5′ terminal phosphorothioate bonds
- Mapping positions of introns in genomic DNA
- Removal of single-stranded DNA, leaving behind the double-stranded DNA in a sample
