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Antarctic Thermolabile UDG
- Uracil DNA glycosylase
- Monofunctional DNA glycosylase that catalyzes the hydrolysis of the N-glycosidic bond from deoxyuridine to release uracil
- Active on ss and dsDNA
- Can be completely inactivated at temperatures above 50°C
- Component of Thermolabile User II Enzyme (NEB #M5508)
- Helps to prevent carryover contamination in LAMP (NEB #M1804, NEB #M1708) and qPCR-related technologies (Luna® Probe One-Step RT-qPCR 4X Mix with UDG (NEB #M3019))