Celonic创新的行业细胞表达平台

 

Celonic提供了两个标准化的细胞系开发平台,可以根据客户的特定需求进行调整。

Celonic创新的行业细胞表达平台

CHOvolution ®是用于在补料分批过程中的单克隆抗体,从而节省时间和成本的高滴度生物生产的平台。如果你正在处理一个去岩藻糖化抗体复合物分子和/或糖基化蛋白,我们人类GEX ®平台的解决方案。

  • 简化的许可模式
    (例如,无销售特许权使用费)
  • 从CHO和GEX衍生产品®平台是在欧洲,美国和亚洲一些临床试验
  • 高扩展稳定性
  • 悬浮液适应无血清EMA和FDA兼容培养基
  • 遵守cGMP准则
  • 在无动物的条件下培养的特性良好的胎儿细胞系

CHOvolution ®

  • 技术Celonic专有SEFEX ®  技术平台
  • 高生产率(能够为mAB输送高达8 g / L的液体)
  • 快速的细胞系开发:多可节省4个月
  • 真正免版税和有约束力的条款

 

 

GEX ®

  • 可以用于特制糖基化的人类细胞
  • 灌注细胞培养的理想选择
  • 针对复杂的生物制药产品进行了优化
  • 在整个细胞培养过程中稳定的产品质量

 

 

我们提供量身定制的解决方案,使您的高潜力分子成为市场成功。我们的综合服务-从细胞系开发到药品的商业化生产-支持您的挑战。

我们的生物解决方案

 

细胞系开发

我们的细胞系开发服务为您的项目提供符合GMP标准且具有成本效益的基础。我们的专有技术,CHOvolution ®和以人为本的GEX ®细胞系,提供解决方案,可根据客户的具体需求进行调整。CHOvolution ®和GEX ®实现高滴度和快速发展轨道。此外,GEX ®能够完*和/或特定的糖基化模式和难以快速蛋白质的高效表达。

看看我们的细胞系技术:

  • 符合GMP标准的细胞系可用于研发和商业市场
  • 基于CHO和人类细胞系的平台技术
  • 糖基化优化(岩藻糖,甘露糖和唾液酸含量)
  • 可制造性和/或可开发性测试
  • 模拟细胞系的产生
  • 4个月内加速细胞系发育
  • 细胞系稳定性研究
  • cGMP细胞库存和存储
  • IND备案文件

USP开发

我们经验丰富的USP开发团队为您提供强大且经济高效的过程开发。从培养基开发到工艺优化,我们都有专门知识来适应和优化工艺,以提高表达效价并增强细胞活力。

  • 媒体开发/优化
  • 进料开发/优化
  • 工艺参数优化
  • 剪应力测试
  • 1升,10升,100升和200升容积的生物反应器系统,用于非GMP开发和可承受的中试运行。

DSP开发

效率是一个良好的下游过程的关键,该过程能始终如一地获得纯净和高质量的产品,同时尽可能多地回收目标蛋白质。Celonic已为抗体建立了下游平台流程,通常可回收超过目标mAB的75%。这样可以节省大量的开发时间和成本。

另外,我们在非抗体产品开发过程中的经验使我们能够在平台适应过程中大限度地提高产品回收率。

  • 适应mAB的纯化工艺
  • 非抗体产品的工艺开发
  • 工艺中间稳定性研究
  • 病毒清除研究
  • 在净化产品从内部CHOvolution丰富的经验®和人类GEX ®细胞系

分析方法开发

我们的分析方法开发部门配备了仪器,例如毛细管电泳和质谱,可提供广泛的相关标准抗体方法。Celonic在开发从头算起非mAb分子的分析方法方面也具有丰富的经验。

我们进行方法开发,包括符合GMP的方法验证和稳定性研究。我们还与在专业表征方法方面拥有丰富经验的合作伙伴合作,以便我们可以在护理服务范围内提供服务。我们拥有一系列分子的专业知识,例如单克隆抗体,抗体片段,融合蛋白,血液因子和酶。Celonic在开发生物仿制药的分析策略(包括参考产品采购)方面也具有丰富的经验。

我们拥有出色的技术专长,并且非常重视我们的合作伙伴和客户。灵活性,快速的个人响应和客户支持是我们日常业务的自然组成部分。

生物测定

终产品的生物活性是生物制药原料药和临床样品规范中的关键特征。因此,为生物活性选择合适的合作伙伴和技术上具有挑战性的基于细胞的测定至关重要。一致的测定性能需要可控的设置,对细胞生理学有深刻理解以及开发完善的特征方法的高技能分析人员。要成功开发此类测定法,需要专业知识,而这只有经验。

Celonic是您在生物测定开发,验证,方法转移和长期测定维护的各个方面的专业专家合作伙伴。我们在Celonic进行GCLP分析开发方面拥有丰富的经验,并且在建立合格且经过验证的产品质量控制方法方面拥有良好的记录。几十年来,我们已成功地将我们的专业知识,熟练程度和专业知识应用于免疫学和常规测定。凭借我们丰富的经验,我们代表您完成测试程序的质量。

我们专注于:

  • 特异性结合测定
  • FcgRIIIa结合测定
  • 抗体依赖性细胞介导的细胞毒性(ADCC)
  • 细胞增殖测定,rhGH,G-CSF和GM-CSF的基于细胞的效力测定
  • 定制的NK细胞细胞毒性测定
  • 定制淋巴细胞增殖测定
  • 评估客户提供的样品

配方开发

ProJect Pharmaceutics *将质量融入配方和过程中,并应用高通量预测稳定性技术(Predictive Formulation Analytics,PFA)来确保生产的一致性。尽早使用此类符合法规的“设计质量”(QbD)步骤将加快和风险中介的下游流程(DSP)开发。它还将产生更稳定的终原料药配方,理想情况下,将导致原料药和产品的配方一致。

我们的优势:

  • 基于基本配方分析,快速识别蛋白质的喜好/不喜欢(舒适区)
  • 在确定的舒适范围内,根据每个DSP步骤的稳定概念的合理设计来优化产量
  • 根据UF / DF的发展原理,即使在高浓度下也可将聚集趋势降至低
  • 基于*的DSP基础工作的加速药品配方

* Celonic的姐妹公司

填充并完成

我们为液体制剂药品提供全面的填充和表面处理服务-从无菌填充到质量控制测试,标签,包装,存储和发布。

我们的解决方案驱动的GMP投诉流程具有的灵活性,*可以满足客户的*需求。在完成300多个GMP灌装批次后,我们的科学家在将产品损失和小瓶废品率控制在低水平方面具有丰富的经验,这对于小批量(1-10 L)的客户而言尤其重要。

  • 高可靠性– 200%的小瓶检查后小于1%的小瓶剔除
  • 小的产品损失–每批次少于150 ml体积损失
  • 可靠的记录–超过300个GMP填充批次的mAb,重组蛋白和疫苗
  • 一站式服务–无菌填充到QC测试,贴标签,发布,存储和运输
  • 批次灵活性–填充100至3000瓶
  • 合规性–符合FDA和EMA

 

ABX 产品目录

 

 

 ABX 
先进的生化化合物制造和开发核医学化学品     

  • 的PET前体和FDG试剂盒供应商
  • 生产和开发PET和SPECT前体和参考标准
  • 制造试剂盒和盒,特别是用于FDG,F-DOPA,FLT,F-胆碱,NaF,F-Miso,FES和FET生产的试剂盒
  • 用于甘露糖三乙酸酯的美国和欧洲药物主文件(DMF)(FDG前体)
  • 用于试剂盒,PET和SPECT前体的其他DMF和技术文件
  • 根据API的GMP定制合成和制造
  • 设计,定制合成和生产 多肽 (根据要求提供GMP质量)
  • 新: 用于68 Ga发电机的 HCl
  • 稳定性研究的表现
  • 新药包和盒式磁带的研发和与制药公司合作的热门实验室
  • 开发放射性示踪剂和标记以及纯化策略
  • ROVER – ABX PET评估软件
  • 18 O-Water FDG等级和GMP等级的分销商
  • 190名专业人士(其中25人拥有博士学位)
  • 在制药条件下洁净室生产和填充

  • 德国制药部门 
    – 美国食品和药物管理局(FDA)审核并接受为GMP API制造商
  • 通过ISO 13485认证

 

Product

CAS No.

ABX 
Product No.

Mannose Triflate, ultra pure

[92051-23-5]

100

Mannose Triflate, ultra pure

[92051-23-5]

101

Mannose Triflate, ultra pure

[92051-23-5]

102

Mannose Triflate PLUS, ultra pure

[92051-23-5]

105

Mannose Triflate PLUS, ultra pure

[92051-23-5]

107

FDG

[86783-82-6] (cyclic form) 
[29702-43-0] (aldehyde form)

1100

6-Deoxy-6-fluoro-D-glucopyranose

[34168-77-9] pyranoside 
[4536-08-7] open-chain

1108

6-FDG precursor

[899808-81-2]

1109

ClDG

[14685-79-1]

1110

Glucose Triflate

[113544-40-4]

1117

MBETG

CAS-RN not yet assigned

1118

MBBTG

[107794-71-8]

1119

FDM

[31077-88-0]

1120

ACY-FDG

[31077-89-1]

1130

1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose

[13100-46-4]

1131

Me-4-FDG precursor

[174618-11-2]

1138

Talose Triflate

CAS-RN not yet assigned

1140

FDGal

[7226-39-3]

1150

DMTr-lyxothymidine

[112501-53-8]

1180

DMTr-Nosyl-lyxothymidine

[444717-20-8]

1190

Dimethoxybenzyl-FLT precursor

[290371-75-4]

1200

Anhydrothymidine-FLT precursor

[191474-13-2]

1210

FLT Ultra Pure

[25526-93-6]

1219

3′-Fluoro-thymidine (FLT)

[25526-93-6]

1220

3′-Iodo-thymidine

[14260-82-3]

1222

5′-O-Benzoyl-2,3′-anhydrothymidine

[70838-44-7]

1230

5′-O-Benzoyl-2,3′-anhydrothymidine (GMP)

[70838-44-7]

1231

3-N-Boc-5′-O-dimethoxytrityl-3′-O-nosyl-thymidine

[444717-23-1]

1240

3-N-Boc-5′-O-dimethoxytrityl-3′-O-nosyl-thymidine (GMP)

[444717-23-1]

1241

2,2′-Anhydrothymidine

[22423-26-3]

1250

2′-Fluoro-thymidine

[122799-38-6]

1260

3-N-Boc-5′-O-dimethoxytrityl-3′-fluorothymidine

[138685-99-1]

1261

DEMM

[93504-92-8]

1280

Thymidine

[50-89-5]

1290

6-Trimethylstannyl-L-DOPA

[143993-90-2]

1300

6-Trimethylstannyl-D,L-DOPA

CAS-RN not yet assigned

1302

6-Trimethylstannyl-D-DOPA

CAS-RN not yet assigned

1303

6-Fluoro-L-DOPA hydrochloride

[144334-59-8]

1310

6-Fluoro-D,L-DOPA hydrochloride

[102034-49-1] (free base)

1311

F-L-DOPA pinacol boronate precursor

CAS-RN not yet assigned

1312

DiBoc-Iodo-L-DOPA

[143993-89-9]

1320

3,4-Di-O-Pivaloyl-L-DOPA

[42567-91-9]

1328

4-O-Pivaloyl-L-DOPA Hydrochloride

[122769-71-5]

1329

4-O-Pivaloyl-L-DOPA

[122551-95-5]

1330

6-Hydroxy-D,L-DOPA

[21373-30-8]

1332

Nucleophilic F-L-DOPA precursor

[1159940-23-4]

1335

n.c.a. Nucleophilic F-L-DOPA precursor

CAS-RN not yet assigned

1336

6-Nitro-L-DOPA hydrogensulfate

[1261156-59-5] (free base)

1337

6-Nitro-Formyl-DOPA HCl

CAS-RN not yet assigned

1338

6-Fluoro-Formyl-DOPA HCl

CAS-RN not yet assigned

1339

TriBoc-L-DOPA methyl ester

[857502-21-7]

1340

TriBoc-D,L-DOPA ethyl ester

CAS-RN not yet assigned

1341

TriBoc-L-DOPA ethyl ester

[203398-46-3]

1342

TriBoc-Iodo-L-DOPA

[853759-55-4]

1350

OMFD precursor ABX004

CAS-RN not yet assigned

1363

OMFD

[114077-01-9]

1369

N-Trifluoroacetyl-3,4-dimethoxy-6-trimethylstannyl-phenethylamine

[170465-14-2]

1370

N-Trifluoroacetyl-3,4-di-tert-butoxycarbonyloxy-6-trimethylstannyl-phenethylamine

[170953-68-1]

1371

6-Fluorodopamine

[71144-39-3]

1380

NITTP

[150196-34-2]

1400

NITTP (GMP)

[150196-34-2]

1401

NITTP (GMP)

[150196-34-2]

1402

Fluoromisonidazole

[13551-89-8]

1410

Desmethylmisonidazole

[13551-92-3]

1420

FETNIM precursor

[163714-99-6]

1430

FETNIM

[204977-05-9]([18F]FETNIM)

1440

1-(2,3-Diacetyl-5-tosyl-(α-D-arabinofuranosyl)-2-nitroimidazole

[494775-35-8]

1450

1-(5-Deoxy-5-fluoro-α-D-arabinofuranosyl)-2-nitroimidazole

[220793-03-3]

1451

N-(2-Tosyloxyethyl)phthalimide

[5460-83-3]

1452

2,3,5,6-Tetrafluorophenyl-2-(2-nitroimidazol-1-yl)acetate

[199734-70-8]

1453

N-(2-Fluoroethyl)-2-(2-nitroimidazol-1-yl)acetamide

[199800-19-6]

1454

ATSM

[63618-91-7]

1455

PTSM

[673-68-7]

1456

CuATSM

[68341-09-3]

1457

NiATSM

[30193-04-5]

1459

(R)-SCH-24518 hydrochloride

[128145-75-5]

1460

(S)-SCH-24518 hydrochloride

[1217462-17-3] 
[135556-21-7] (free base)

1462

SCH-23390 hydrochloride

[125941-87-9]

1464

SCH-23388 hydrochloride

[1217443-99-6] 
[73445-63-3] (free base)

1466

(R)-(-)-Norapomorphine hydrobromide

[115017-61-3]
[478-76-2] (free base)

1477

(+)-Desmethyl-NNC112

[221132-62-3]

1480

(+)-NNC112

[125341-24-4]

1490

(S)-O-Desmethylraclopride hydrobromide

[113310-88-6]

1500

(R)-O-Desmethylraclopride hydrobromide

[113310-87-5]

1501

(R,S)-O-Desmethylraclopride hydrobromide

[857335-91-2] (free base)

1502

(S)-O-Desmethylraclopride

[119670-11-0]

1510

Raclopride

[84225-95-6]

1520

Tin-epidepride precursor

[135382-47-7]

1521

Epidepride

[107188-87-4]

1522

FLB 604

[128600-22-6]

1530

FLB 457

[107188-74-9]

1540

Tosyl-Fallypride

[166173-74-6]

1550

Fallypride

[166173-78-0]

1560

Tosyl-Desmethoxyfallypride

[713135-14-9]

1570

Desmethoxyfallypride

[166173-81-5]

1580

N-Mesitylenesulfonyloxy-ethyl-spiperone

[128584-73-6]

1590

Fluoroethylspiperone

[106114-42-5]

1591

D-threo-N-NPS-Ritalinic acid

[159701-28-7]

1592

D-threo-Methylphenidate hydrochloride

[19262-68-1]

1593

(R)-N-Desmethyl PK11195

[157809-85-3]

1600

(S)-PK 11195

[205934-45-8]

1609

(R)-PK11195

[205934-46-9]

1610

(R,S)-PK11195

[85532-75-8]

1611

(S)-N-Desmethyl PK11195

[157809-86-4]

1620

(R,S)-N-Desmethyl PK11195

[124236-61-9]

1640

(+)-9-MeO-HNO hydrochloride

[99833-85-9]

1642

(+)-HNO hydrochloride

[858517-21-2]

1643

(+)-PHNO hydrochloride

[99705-65-4]

1645

(+)-F-PHNO

[905963-70-4]

1646

(+)-HNO hydrochloride (GMP)

[858517-21-2]

1647

PBR28 precursor

[1005325-42-7]

1652

PBR28 standard

[253307-72-1]

1653

FEPPA precursor

[1095267-89-2]

1654

FEPPA standard

[1095267-90-5]

1655

Azidomazenil

[91917-65-6]

1680

Desmethylazidomazenil

[143188-51-6]

1681

Nitromazenil

[84377-97-9]

1690

Mazenil pinacol boronate

CAS-RN not yet assigned

1691

Desmethylflumazenil

[79089-72-8]

1700

Flumazenil

[78755-81-4]

1710

Flumazenil acid

[84378-44-9]

1720

Tosyloxyethylflumazenil

[676437-17-5]

1721

Fluoroethylflumazenil

[676437-19-7] ([18F]FFMZ)

1730

Harmol

[487-03-6]

1753

Harmine

[442-51-3]

1755

(R)-Metomidate hydrochloride

[66392-64-1]

1760

(S)-Metomidate hydrochloride

[66392-65-2]

1762

(R)-Etomidate

[33125-97-2]

1770

(R)-Desethyl-Etomidate

[56649-48-0]

1780

(S)-Desethyl-Etomidate

[56649-49-1]

1782

(R)-Fluoroethyl-Etomidate

[960403-07-0]

1790

Nitro-Altanserin

[139418-53-4]

1800

Altanserin

[76330-71-7]

1810

Nitro-Setoperone

[113981-16-1]

1820

Setoperone

[86487-64-1]

1830

MDL105725

[189192-18-5]

1840

MDL100907

[139290-65-6]

1850

MDL100151

[139290-69-0]

1860

MDL100907 tartrate salt

[139290-65-6] (free base)

1870

SB206453

[148702-73-2]

1880

SB206453 (GMP)

[148702-73-2]

1881

SB207145

[148702-79-8]

1882

MMSE

[177714-21-5]

1900

16α-Fluoroestradiol

[92817-10-2]

1910

FDHT precursor

[141664-05-3]

1916

FDHT standard

[141663-88-9]

1918

TNB-Androstanone

CAS-RN not yet assigned

1919

FFNP precursor

[445379-33-9]

1926

FFNP standard

[160388-33-0]

1928

3-O-Trityl-6-O-desmethyl-diprenorphine

[157891-92-4]

2000

Diprenorphine hydrochloride

[16808-86-9]

2010

Diprenorphine

[14357-78-9]

2020

3-O-Trityl-diprenorphine

[157891-91-3]

2030

6-O-Fluoroethyl-6-O-desmethyl-diprenorphine

CAS-RN not yet assigned

2040

6-O-Fluoroethyl-6-O-desmethyl-3-O-trityl-diprenorphine

CAS-RN not yet assigned

2050

3-O-Trityl-6-O-desmethyl-phenethyl-orvinol

[1187551-69-4]

2051

Phenethyl-orvinol

[14521-98-3

2052

6-O-(2-Fluoroethyl)-6-O-desmethyl-phenethyl-orvinol

CAS-RN not yet assigned

2053

3-O-Trityl-6-O-desmethyl-buprenorphine

[157891-93-5]

2055

Buprenorphine hydrochloride

[53152-21-9]

2056

(S)-(-)-Normethylcarbamoyl-GR 103545

[260992-21-0]

2060

(R)-(+)-Normethylcarbamoyl-GR 103545

[199470-02-5]

2061

Normethylcarbamoyl-GR 89696

[126766-48-1]

2062

GR 89696 fumarate

[126766-32-3]

2070

(R)-(-)-GR103545 fumarate

[126766-43-6]

2071

(S)-(+)-GR89696 fumarate

[150133-21-4]

2072

Acetic acid piperidin-4-yl ester hydrochloride

[94886-04-1]

2110

Acetic acid 1-methyl-piperidin-4-yl ester hydrochloride

[58931-63-8]

2120

Propionic acid piperidin-4-yl ester hydrochloride

[219859-83-3]

2130

Propionic acid 1-methyl-piperidin-4-yl ester hydrochloride

[64219-77-8]

2140

Butyric acid piperidin-4-yl ester hydrochloride

CAS-RN not yet assigned

2150

Butyric acid 1-methyl-piperidin-4-yl ester hydrochloride

CAS-RN not yet assigned

2160

L-Homocysteine

[6027-13-0]

2200

D,L-Homocysteine

[454-29-5]

2205

L-Homocysteine thiolactone hydrochloride

[31828-68-9]

2210

L-Methionine

[63-68-3]

2220

D-Methionine

[348-67-4]

2229

D,L-Methionine

[59-51-8]

2230

N-Boc-trans-4-tosyloxy-L-proline methyl ester

[88043-21-4]

2300

N-Boc-trans-4-mesyloxy-D-proline tert-butyl ester

CAS-RN not yet assigned

2301

N-Boc-cis-4-tosyloxy-L-proline methyl ester

CAS-RN not yet assigned

2310

cis-4-Fluoro-L-proline

[2438-57-5]

2320

cis-4-Fluoro-D-proline hydrochloride

[913820-71-0] (free amino acid)

2321

trans-4-Fluoro-L-proline

[2507-61-1]

2330

rac [11C]-AIB precursor

[115134-32-2] (S-AIB-precursor)

2340

S-[11C]-AIB precursor

[115134-32-2]

2342

Desmethylcar* acid

[186022-53-7]

2390

Desmethylcar*, sodium salt

[98598-82-4]

2400

Fluoroethyl-Car*

[904892-57-5]

2420

Fluoroethyl-Car* hydrochloride

[1007840-96-1]

2421

(S)-FPSPPA

[1283095-64-6]

2450

(R)-FPSPPA

[1283095-67-9]

2460

(S)-Methyl-FPSPPA

[1283095-70-4]

2470

(R)-Methyl-FPSPPA

[1283095-73-7]

2480

(R)-Desisopropylcarazolol

[143412-41-3]

2500

(S)-Desisopropylcarazolol

[143412-40-2]

2510

(R,S)-Desisopropylcarazolol

[72955-96-5]

2511

(R)-Carazolol

[78859-34-4]

2520

(S)-Carazolol

[78859-33-3]

2530

(R,S)-Carazolol

[57775-29-8]

2540

(S)-N-Desisopropylpropranolol

[88547-38-0]

2550

GB 99

[116784-78-2]

2570

GB 67

[116784-70-4]

2580

(S)-1-(2-Amino-3-nitrophenoxy)-3-tert-butylamino-propan-2-ol

[132059-12-2]

2590

4-(2-Keto-3-methyl-1-benzimidazolinyl)piperidine

[53786-10-0]

2700

Cyclopropyl-p-nitrophenyl ketone

[93639-12-4]

2750

FNMB

[133066-70-3]

2760

3-O-Benzyl-naltrindole

[161532-22-5]

2800

N-Methylnaltrindole

[111555-57-8]

2810

QNB

[6581-06-2]

2830

Me-QNB

[71861-83-1]

2840

Benzyl-14-(R,S)-tosyloxy-6-thiaheptadecanoate

[137564-70-6]

2850

14-(R,S)-Fluoro-6-thiaheptadecanoic acid

[137564-72-8]

2860

2-O-(Trifluoromethylsulfonyl)-1,3,5-tri-O-benzoyl-α-L-ribofuranose

[339091-18-8]

2869

2-O-(Trifluoromethylsulfonyl)-1,3,5-tri-O-benzoyl-α-D-ribofuranose

[97614-41-0]

2870

5-Ethyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine

[31167-05-2]

2871

5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine

[7288-28-0]

2872

Bis(trimethylsilyl)cytosine

[18037-10-0]

2873

L-FEAU

[171720-95-9]

2874

α-L-FEAU

CAS-RN not yet assigned

2875

FEAU

[83546-42-3]

2876

αFEAU

CAS-RN not yet assigned

2877

FMAU

[69256-17-3]

2878

αFMAU

[97672-34-9]

2879

FTRU

[336881-26-6]

2880

FTAU

[213136-14-2]

2890

FAU

[69123-94-0]

2900

FIAU

[69123-98-4]

2910

FUdR

[784-71-4]

2920

Di-THP-nosyl-AUR

[1000816-92-1]

2921

FIRU

[55612-21-0]

2922

FAC

[56632-83-8]

2930

αFAC

CAS-RN not yet assigned

2931

3′-Fluoro-2′,3′-dideoxyuridine

[41107-56-6]

2940

5-Trimethylstannyl-2′-deoxyuridine

[146629-34-7]

2948

IUdR

[54-42-2]

2949

2′-Deoxy-L-uridine

[31501-19-6]

2950

Nitro-Xeloda

[865474-03-9]

2952

Xeloda

[154361-50-9]

2953

2′,3′-Didehydro-3′-deoxythymidine

[3056-17-5]

2954

5-Fluorouracil precursor

[219638-33-2] (cation)

2958

Tosyl-FHBG

[206067-84-7]

2960

FHBG

[206067-83-6]

2970

N,O-Di-Boc-2-TMSn-L-tyrosine ethyl ester

[400885-40-7]

3000

2-Fluoro-tyrosine

[78709-81-6]

3010

2-Iodo-tyrosine

[78853-38-0]

3020

Thyronamine Hydrochloride

[5221-18-1]

3035

3-Iodothyronamine Hydrochloride

[788824-64-6]

3036

TET

[478037-15-9]

3050

TET (GMP)

[478037-15-9]

3051

TET (GMP)

[478037-15-9]

3052

FET hydrochloride

[854750-33-7] (free base)

3061

D-FET hydrochloride

[223463-90-9] (free base)

3071

(L)-HET hydrochloride

[481052-68-0] (free base)

3081

N-Trifluoroacetyl-5-acetoxy-2-trimethylstannyl-phenylalanine ethyl ester

[148613-10-9]

3100

N,O-Di-Boc-2-TMSn-m-tyrosine ethyl ester

[845882-24-8]

3110

2-Fluoro-m-Tyrosine

[148613-12-1]

3130

2-Iodo-α-methyl-p-tyrosine

CAS-RN not yet assigned

3180

3-Iodo-α-methyl-p-tyrosine

[4298-17-3]

3190

(S)-tert-Butyl 2-((tert-butoxycarbonyl) amino)-4-Iodobutanoat

[161370-66-7]

3191

WAY 100634

[155204-28-7]

3200

WAY 100635

[146714-97-8]

3210

Desmethyl-WAY100635

[146715-34-6]

3220

Desmethyl-WAY 100634

[146714-76-3]

3230

Nitro-MPPF

[155204-27-6]

3240

MPPF

[155204-26-5]

3250

Desmethyl-MPT

[874471-23-5]

3260

MPT

[179756-59-3]

3270

TAP

[213766-21-3]

3300

IAP

[213764-92-2]

3310

Nitro-AP

[209530-92-7]

3320

FAP tartrate

[209530-93-8] (free base)

3340

TMA-AP

[233766-75-1]

3350

(-)-Flubatine standard

[845642-53-7]

3351

(-)-Flubatine precursor

[1421915-93-6]

3353

(-)-Flubatine precursor (GMP)

[1421915-93-6]

3354

(+)-Flubatine standard

[845642-52-6]

3355

(+)-Flubatine precursor

CAS-RN not yet assigned

3357

(+)-Flubatine precursor (GMP)

CAS-RN not yet assigned

3358

ASEM precursor

[1456877-71-6]

3371

Metaraminol (free base)

[54-49-9]

3380

Metaraminol bitartrate

[33402-03-8]

3390

MHED hydrochloride

[24493-89-8]

3400

Desmethyl-GR 205171

[180574-25-8]

3500

GR 205171

[168266-90-8]

3510

Desmethyl-GR 205171 Dihydrochloride

[262598-97-0]

3520

GR 205171 Dihydrochloride

[168266-51-1]

3530

Desmethyl-CNS 5161

[160754-78-9]

3540

CNS 5161

[160754-76-7]

3550

Desmethyl ABP688

[849469-03-0]

3560

Desmethyl ABP688 (GMP)

[849469-03-0]

3561

ABP688

[924298-51-1]

3570

FPEB precursor

[1031370-96-3]

3571

FPEB standard

[864063-10-5]

3572

ISOM

[945992-43-8]

3590

ISOF

[851705-46-9]

3591

Desmethyl-SCH-442416

[188112-92-7]

3700

SCH-442416

[316173-57-6]

3710

Desmethyl-MK-8278

[879368-41-9]

3720

CPTPX

[478173-67-0]

3750

CPFPX

[200557-18-2]

3751

(-)-2-beta-Carbomethoxy-3-beta-(4-fluorophenyl)tropane

[50370-56-4]

4000

(-)-2-beta-Carbomethoxy-3-beta-(4-fluorophenyl)nortropane

[127648-30-0]

4020

(-)-2-beta-Carbomethoxy-3-beta-(4-iodophenyl)tropane

[135416-43-2]

4030

TMS-CT

[158111-10-5]

4040

TBS-CT

[136794-88-2]

4041

(-)-2-beta-Carbomethoxy-3-beta-(4-iodophenyl)nortropane

[136794-87-1]

4050

(-)-2-beta-Carbomethoxy-3-beta-(phenyl)tropane

[50372-80-0]

4060

CITFES

[180045-77-6]

4100

CITFE

[155798-01-9]

4110

CITTP Tosylate

[186381-39-5] (free base)

4122

CITFP

[155797-99-2]

4130

TBSCT-FP

[479642-48-3]

4132

beta-CIT acid

[141807-58-1]

4140

2-FE-beta-CIT

[398497-81-9]

4150

PE2I acid

[311351-26-5]

4160

PE2I tin precursor

[188680-65-1]

4165

PE2I

[188680-71-9]

4170

TEO-PE2I

[1391711-43-5]

4172

FE-PE2I

[949091-68-3]

4173

Nor-beta-CClT

[146725-33-9]

4180

FECNT

[281667-94-5]

4190

Altropane acid

[335104-67-1]

4200

Altropane acid hydrochloride

[335104-67-1] (Altropane acid free amine)

4201

Altropane

[180468-34-2]

4210

Altropane hydrochloride

[180468-34-2] (free base)

4211

Norbenztropine

[28404-87-7]

4230

Benztropine Mesylate

[132-17-2]

4231

MASB

[296774-10-2]

4300

MASB (GMP)

[296774-10-2]

4301

DASB

[627490-01-1]

4310

DASB (GMP)

[627490-01-1]

4311

AFM precursor

[844699-84-9] (free base)

4320

AFM standard

[627490-40-8] (free base)

4330

(+)-McN 5652 Thiobutyrate

[167548-65-4] (free base)

4360

(+)-McN 5652

[259145-56-7] 
[103729-16-4] (free base)

4370

(-)-McN 5652

[262352-33-0] 
[103729-13-1] (free base)

4380

(+)-Fluoromethyl-McN 5652

[432038-21-6] (free base)

4381

FBAM precursor

[937025-28-0]

4383

FBAM standard

[937025-29-1]

4384

CPTMA

[124915-01-1]

4385

CMTMA

[51570-69-5] (CMTMA cation)

4386

TBAB

[660845-84-1]

4389

PMBAB

[223699-69-2]

4390

FB precursor

[124915-06-6]

4391

SFB

[66134-67-6]

4392

[18F]FPyBrA/[18F]FPyME precursor

[640749-64-0]

4393

FPyME standard

[640749-61-7]

4394

[18F]FPyKYNE precursor

[1161009-68-2]

4396

FPyKYNE

[1161009-63-7]

4397

FBEM precursor

[146474-00-2]

4398

FBEM standard

[1089194-09-1]

4399

(2S,3S)-N-Boc-norethylreboxetine

[754988-84-6]

4400

(2S,3S)-N-Boc-carboxylreboxetine

[1016545-04-2]

4402

(2S,3S)-Carboxylreboxetine fluoroethyl ester trifluoroacetate

CAS-RN not yet assigned

4403

Methylreboxetinecarboxylate

[1016545-13-3] (free base)

4405

(2S,3S)-Methylreboxetine

[105018-14-2]

4406

(2S,3S)-Desethylreboxetine

[252570-31-3]

4407

Norbinaltorphimine dihydrochloride

[113158-34-2] 
[105618-26-6] (free base)

4500

(-)-TEBV

[153215-71-5]

4600

(-)-FEBV

[153215-70-4]

4610

(±)-9-O-Desmethyl-α-dihydrotetrabenazine

[5220-98-4]

4700

(+)-9-O-Desmethyl-α-dihydrotetrabenazine

CAS-RN not yet assigned

4710

(-)-9-O-Desmethyl-α-dihydrotetrabenazine

CAS-RN not yet assigned

4720

(±)-α-Dihydrotetrabenazine

[3466-75-9]

4730

(±)-beta-Dihydrotetrabenazine

CAS-RN not yet assigned

4731

(±)-Tetrabenazine

[58-46-8]

4732

(±)-9-O-Desmethyl-tetrabenazine

[149183-89-1]

4733

Aminothiadiazine

[319002-53-4]

4900

Chlorothiadiazine

[194086-61-8]

4910

DMTEAN

[259739-02-1]

5000

DFEAN

[1161260-63-4] ([18F]DFEAN)

5010

DMEAN

[259739-01-0]

5020

DMFEAN

[590365-47-2]

5030

6-OH-BTA-0

[178804-18-7]

5100

6-OH-BTA-0 (GMP)

[178804-18-7]

5101

6-MOMO-BTA-0

[566170-03-4]

5110

6-MOMO-BTA-0 (GMP)

[566170-03-4]

5111

6-OH-BTA-1 hydrochloride

CAS-RN not yet assigned

5120

6-MeO-BTA-0

[43036-17-5]

5130

6-OH-BTA-1 (free base)

[566169-93-5]

5140

6-O-Tosyloxyethyl-CBT

[1392498-16-6]

5149

[18F]Lansoprazole Precursor

[1613520-76-5]

5150

Astemizole

[68844-77-9]

5165

O-Desmethyl Astemizole

[73736-50-2]

5166

Desmethyl-PD 153035

[295330-61-9]

5200

PD 153035

[153436-54-5]

5210

Norverapamil

[67018-85-3]

5600

(-)-Norverapamil

[123931-31-7]

5620

(+)-Verapamil hydrochloride

[38176-02-2]

5630

N-Demethylrifampicin

[13292-45-0]

5700

Rolipram

[61413-54-5]

6000

(S)-(+)-Rolipram

[85416-73-5]

6010

(R)-(-)-Rolipram

[85416-75-7]

6020

Desmethyl-Rolipram

[150519-28-1]

6030

(S)-(+)-Desmethyl-Rolipram

[347148-60-1]

6040

(R)-(-)-Desmethyl-Rolipram

[347148-59-8]

6050

Dimethylaminoethanol

[108-01-0]

6100

Fluoroethylcholine tosylate

[479407-07-3]

6120

Fluoromethylcholine chloride

[459424-38-5]

6130

Fluoromethylcholine bromide

CAS-RN not yet assigned

6140

Bromocholine bromide

[28508-20-5]

6141

Choline chloride

[67-48-1]

6150

Fluoroethylcholine chloride

[479407-08-4]

6160

Choline iodide

[17773-10-3]

6170

DMMB

[40968-70-5]

6173

BHTMEDA

[60168-37-8]

6174

Dibromoethane

[106-93-4]

6175

Dibromomethane

[74-95-3]

6176

Bis(tosyloxy)methane

[24124-59-2]

6177

1,2-Bis(nosyloxy)ethane

[25297-82-9]

6179

1,2-Bis(tosyloxy)ethane

[6315-52-2]

6180

2-Bromoethyl nosylate

[52331-22-3]

6181

2-Bromoethyl triflate

[103935-47-3]

6182

2-Bromoethyl tosylate

[19263-21-9]

6183

2-Fluoroethyl tosylate

[383-50-6]

6184

Bis(tosyl)-1,4-butanediol

[4724-56-5]

6185

1,4-Bis(tosyloxy)but-2-yne

[6337-59-3]

6186

3-Fluoropropyltosylate

[312-68-5]

6190

1,3-Propane-di-tosylate

[5469-66-9]

6191

Fluoromethyl tosylate

[114435-86-8]

6194

Ethyl (p-tosyloxy)acetate

[39794-75-7]

6200

Potassium fluoroacetate

[23745-86-0]

6210

Sodium fluoroacetate

[62-74-8]

6211

DBCO-SCN

CAS-RN not yet assigned

6221

1-Tosyloxy-3-butyne

[23418-85-1]

6301

1-Tosyloxy-4-pentyne

[77758-50-0]

6302

1-Tosyloxy-5-hexyne

[76911-01-8]

6303

Tosyl-propargyl-diethylene glycol

[1119249-30-7]

6305

Tosyl-propargyl-triethylene glycol

[888009-94-7]

6307

Fluoro-propargyl-triethylene glycol

[1003005-81-9] ([18F]Fluoro-propargyl-triethylene glycol)

6308

3-(4-Azidophenoxy)propyl methansulfonate

[943726-04-3]

6320

(S)-O-Tosyl-1,2-Epoxybutanol

[91111-12-5]

6351

Dimethyl-8-acetyl-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate

[79465-83-1]

6500

α-Methyl-L-tryptophan

[16709-25-4]

6510

Dimethyl-8-phenylsulfonyl-5-phenylsulfonyloxy-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate

[150804-39-0]

6520

5-FEHTP hydrochloride

[1215091-03-4] (free base)

6532

MIBG Hemisulfate

[87862-25-7] 
[80663-95-2] (free base)

7000

MIBG Hemisulfate (GMP)

[87862-25-7]

7001

MTMSBG

[143773-92-6] (free base)

7010

TMSnBG

[1000875-21-7]

7012

SGMIB Standard

[344791-53-3] (free base)

7014

SGMIB Precursor

[344791-59-9]

7015

CNS 1261

[341032-67-5]

7020

TBS-CNS 1261

[765890-24-2]

7030

MFBG pinacol boronate precursor

CAS-RN not yet assigned

7033

MFBG hydrochloride

[1246547-53-4]

7034

Mebrofenin

[78266-06-5]

7050

Disofenin

[65717-97-7]

7060

Succinimidyl-N-Boc-Hynic

[133081-26-2]

7080

Succinimidyl-Hynic hydrochloride

[133081-27-3] 
[167639-20-5] (free base)

7090

S-Benzoyl-MAG-3

[103725-47-9]

7100

MAG 3

[66516-09-4]

7110

(Benzoylmercapto)acetic acid

[6398-74-9]

7111

BMEDA

[93798-62-0]

7150

MDP

[1984-15-2]

7160

HMDP

[14255-61-9]

7161

EDTMP

[1429-50-1]

7165

MIBI

[109434-22-2]

7200

Copper tetraMIBI tetrafluoroborate [Cu(MIBI)4]BF4

[103694-84-4]

7210

Copper tetraMIBI tetrafluoroborate (GMP)

[103694-84-4]

7211

Zinc-TBI

[104676-71-3]

7220

EC

[14344-48-0]

7250

ECD

[14344-58-2] 
[121251-02-3] (free base)

7260

TFP-N-sucDf-Fe

[676596-40-0]

7270

TACN

[58966-93-1]

7281

PrP9

[1242003-07-1] (water free compound)

7284

Cyclen

[294-90-6]

7290

DOTA

[60239-18-1]

7300

DOTAEt

[137076-50-7]

7301

Tetrofosmin

[127502-06-1]

7310

Disodium sulfosalicylate

[56343-01-2]

7312

BPAMD

[872469-60-8]

7320

HBED-CC-tris(tBu)ester

CAS-RN not yet assigned

7330

HBED-CC-di(tBu)ester

CAS-RN not yet assigned

7331

TRODAT

[189950-11-6] (free base)

7400

S-(-)-BZM

[84226-04-0]

7500

S-(-)-IBZM

[84226-06-2]

7510

Gallium Citrate (complex)

CAS-RN not yet assigned

7520

16-Iodohexadecanoic acid

[2536-36-9]

7600

Cryptand 222

[23978-09-8]

800

Lithium Aluminium Hydride in THF bulk

[16853-85-3]

801

Lithium aluminium hydride (0.1 M in THF)

[16853-85-3]

802

Lithium aluminium hydride (0.25 M in THF)

[16853-85-3]

803

Lithium aluminium hydride (0.05 M in THF)

[16853-85-3]

804

Tetrabutylammonium Hydrogen Carbonate (0.075 M) – Aqueous solution, stabilized with ethanol

[17351-62-1]

808

Pentadecylmagnesium bromide 0.5 M in diethyl ether

[78887-70-4]

831

Lithium aluminium hydride (0.1 M in THF)

[16853-85-3]

832

Fmoc-Lys(ivDde)-OH

[204777-78-6]

9500

PMPA

[173039-10-6]

9510

Ubiquicidin (29-41) acetate

[216867-99-1] (net peptide)

9600

DOTA-Ubiquicidin (29-41) acetate

CAS-RN not yet assigned

9601

Scrambled Ubiquicidin (29-41)

CAS-RN not yet assigned

9602

NOTA-Ubiquicidin (29-41) acetate

CAS-RN not yet assigned

9603

DOTATOC (GMP)

[204318-14-9]

9702

Ga-DOTA-TOC acetate

[293295-70-2]

9703

Y-DOTA-TOC

[293295-66-6]

9704

Lu-DOTA-TOC

[321835-55-6] ([177Lu]-DOTA-TOC)

9705

DOTA-NOC acetate

[619300-53-7] (net peptide)

9712

AMBA acetate

[721937-56-0] (net peptide)

9714

DOTA-[Pro1,Tyr4]bombesin (1-14)

[593287-40-2] (net peptide)

9715

DOTA-NOC acetate (GMP)

[619300-53-7] (net peptide)

9716

Ga-DOTA-NOC

[1027785-95-0] 
[1040397-47-4] [68Ga]DOTA-NOC

9717

NODAGA-NOC acetate

CAS-RN not yet assigned

9718

HYNIC-TOC trifluoroacetate

[257943-19-4] (net peptide)

9721

HYNIC-NOC trifluoroacetate

CAS-RN not yet assigned

9730

Pentreotide trifluoroacetate

[138661-02-6] (net peptide)

9740

DTPA-TOC trifluoroacetate

[147790-81-6] (net peptide)

9744

Octreotide acetate

[79517-01-4] 
[83150-76-9] (net peptide)

9750

[Nal3]Octreotide acetate

[848820-27-9] (net peptide)

9752

TETA-Octreotide acetate

[226084-96-4] (net peptide)

9760

NOTA-Octreotide trifluoroacetate

CAS-RN not yet assigned

9762

NOTA-NOC acetate

CAS-RN not yet assigned

9765

Gluc-[Lys0,Lys(ivDde)5]-TOCA

CAS-RN not yet assigned

9771

DOTA-TATE acetate (GMP)

[177943-89-4]

9772

Ga-DOTA-TATE

[777842-51-0] 
[293295-75-7] [68Ga]DOTA-TATE

9773

[Tyr3]Octreotate acetate

[302794-43-0] (net peptide)

9774

Gluc-Lys(FP)-TOCA

CAS-RN not yet assigned

9778

ICG-TATE

CAS-RN not yet assigned

9782

Galacto-RGD

[922175-70-0] (net peptide)

9790

Fluoropropionyl-Galacto-RGD

CAS-RN not yet assigned

9800

NOTA-RGDfK acetate

CAS-RN not yet assigned

9802

Ga-NODAGA-RGD dimer

CAS-RN not yet assigned

9803

NODAGA-RGD dimer acetate

CAS-RN not yet assigned

9804

NODAGA-RGD trifluoroacetate

CAS-RN not yet assigned

9805

NODAGA-RGD (GMP)

CAS-RN not yet assigned

9806

Ga-NODAGA-RGD

CAS-RN not yet assigned

9807

[Tyr3]Octreotide acetate

[103667-46-5] (net peptide)

9810

NODAGA-AMBA trifluoroacetate

CAS-RN not yet assigned

9814

NOTA-AMBA trifluoroacetate

CAS-RN not yet assigned

9815

[Pro1,Tyr4]bombesin (1-14)

[832724-21-7] (net peptide)

9816

Lanreotide trifluoroacetate

[108736-35-2] (net peptide)

9820

DOTA-Lanreotide acetate

[213187-44-1] (net peptide)

9831

HYNIC-Lanreotide trifluoroacetate

CAS-RN not yet assigned

9836

4-Formyl-N,N,N-Trimethylanilinium triflate

[124915-02-2]

9850

DOTA-NAPamide trifluoroacetate

[935886-72-9] (net peptide)

9855

DOTA-Sargastrin

CAS-RN not yet assigned

9857

Cyclo-RGDfK

[161552-03-0]

9860

Cyclo-RGDfK dimer trifluoroacetate

[250612-47-6] (net peptide)

9861

DOTA-RGDfK dimer acetate

[250612-06-7] (net peptide)

9862

DOTA-cyclo(RGDfK) acetate

[909024-55-1] (net peptide)

9863

HYNIC-cyclo(RGDfK) trifluoroacetate

[366455-78-9] (net peptide)

9864

DTPA-Bn-cyclo(RDGfK) dimer trifluoroacetate

[1004322-97-7]

9866

HYNIC-cyclo(RGDfK) dimer trifluoroacetate

[500166-11-0]

9867

[Tyr3,Lys5(Boc)]octreotide acetate

[147790-89-4] (net peptide)

9900

[Lys5(Boc)]octreotate acetate

[133304-78-6] (net peptide)

9901

[Lys5(Boc)]lanreotide acetate

[182482-12-8] (net peptide)

9902

[Nal3,Lys5(Boc)]octreotide acetate

CAS-RN not yet assigned

9903

5(6)-FAM-TATE

CAS-RN not yet assigned

9908

PSMA-11 (GMP)

[1366302-52-4]

9919

PSMA-11

[1366302-52-4]

9920

PSMA-11 (GMP)

[1366302-52-4]

9921

GaPSMA-11

CAS-RN not yet assigned

9922

PSMA-10

CAS-RN not yet assigned

9923

DCFPyL reference standard

[1423758-00-2]

9925

PSMA-617

CAS-RN not yet assigned

9933

PSMA-617 (GMP)

CAS-RN not yet assigned

9934

GaPSMA-617

CAS-RN not yet assigned

9935

LuPSMA-617

CAS-RN not yet assigned

9936

deprotected DCFPyL precursor

CAS-RN not yet assigned

9941

PSMA-1007 precursor

CAS-RN not yet assigned

9943

PSMA-1007 reference standard

CAS-RN not yet assigned

99433

DOTA-Substance P

CAS-RN not yet assigned

9960

DOTA-Substance P

CAS-RN not yet assigned

9960

 

 

 

 

 

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