A protein involved in the regulation of actin dynamics
Fact Sheet Cat. No. 307 011
Monoclonal mouse antibody
Cat. No. 307 011 IgG, unlabeled
100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20°C until use.
Applications
WB: 1 : 100 up to 1 : 2000 (AP staining) blot IP: yes ICC: 1 : 100 image IHC: not tested yet
DCs are important components both of the IgE-mediated type I allergies mostly affecting respiratory and mucosal tissue, and of the type IV skin contact hypersensitivity reactions. Their functions in allergic disease encompass antigen-presentation properties resulting in allergen-specific T cell responses and properties influencing the Th1/Th2 balance and the induction of regulatory T cells (1). SeveralDENDRITICS antibodies should be useful for in vitro studies of the impact of allergen on shaping the immunoregulatory properties of human DCs.
Derp-2
DDX0210 H.AK6.A3.F4 Derp -2 人IgG1k
人单克隆抗体
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抑制人IgE与Bet V1的结合
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增强人类IgE与Bet V1的结合
DDX0052 202B8.03(mAb7) 桦木花粉Bet V1 小鼠IgG1
Bet V1免疫渗透
DDX0070 H.G27E9B1(别名BAB4) 桦木花粉Bet V1 Human IgG2k
人单克隆抗体,免疫沉淀
DDX0071 H.G26F6B2.06 桦树花粉Bet V1 人类IgG3
人单克隆抗体
DDX0072 H.G11A9F3.03(别名BAB3) 桦木花粉Bet V1 人类IgG4k
人单克隆抗体,免疫沉淀
DDX0073 H.G28C10.01(别名BAB5) 桦木花粉Bet V1 Human IgG4k
人单克隆抗体
DDX0074 H.G5F2A4.09(别名BAB1) 桦木花粉Bet V1 人IgG1k
人单克隆抗体; 阻止组胺释放
DDX0075 H.G3A3C2.04 桦木花粉Bet V1 人IgG2
人单克隆抗体
DDX0076 H.G17E7A1(别名BAB2) 桦木花粉Bet V1 人类IgG4
人单克隆抗体; 增加组胺释放
抗原家族
神经细胞
治疗性抗体
人血小板抗原
整合
C型凝集素受体
外周血单核细胞
Toll样受体/衔接蛋白
病毒
过敏原
直流迁移
细胞因子和受体
抗原呈递
DC细胞亚型
过敏原
DCs是IgE介导的I型过敏的重要组成部分,其主要影响呼吸和粘膜组织,以及IV型皮肤接触性超敏反应。它们在过敏性疾病中的功能包括抗原呈递特性,导致过敏原特异性T细胞反应和影响Th1 / Th2平衡和调节性T细胞诱导的性质(1)。几个DENDRITICS抗体 应该是有用的体外 过敏原对塑造人类DC的免疫调节性能影响的研究。 参考文献 1.Akbari O和Umetsu DT。,Role of regulatory dendritic cells in allergy and asthma,2005 Curr Allergy Asthma Rep 5:56-61
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桦木花粉Bet V1
DDX0050 102H10.05(mAb2) 桦木花粉Bet V1 小鼠IgG1
抑制人IgE与Bet V1的结合
DDX0051 110G10.01(mAb13) 桦木花粉Bet V1 小鼠IgG1
增强人类IgE与Bet V1的结合
DDX0052 202B8.03(mAb7) 桦木花粉Bet V1 小鼠IgG1
Bet V1免疫渗透
DDX0070 H.G27E9B1(别名BAB4) 桦木花粉Bet V1 Human IgG2k
人单克隆抗体,免疫沉淀
DDX0071 H.G26F6B2.06 桦树花粉Bet V1 人类IgG3
人单克隆抗体
DDX0072 H.G11A9F3.03(别名BAB3) 桦木花粉Bet V1 人类IgG4k
人单克隆抗体,免疫沉淀
DDX0073 H.G28C10.01(别名BAB5) 桦木花粉Bet V1 Human IgG4k