尿激酶型纤溶酶原激活物(Urokinase type Plasminogen Activator (uPA) ),uPA是一种丝氨酸蛋白水解酶。小鼠uPA基因位于第10条染色体长臂上,其长度为6.5KD,由11个外显子构成,可转录成24KB的成熟的mRNA,初始翻译产物为前尿激酶原(含431个氨基酸残基),除去20个氨基酸残基的信号肽后即为细胞分泌的尿激酶原(pro-uPA),在158LYs位处劈裂,则成为由二硫键连结的双链活性型结构,即20×103的A链和34×103的B链。C端的A链包括一个Kringle区和表皮生长因子(EGF)功能区,表皮生长因子功能区能介导与特异的受体结合,去掉此功能区,其仍具有激活纤溶酶原作用,,但却无与受体结合的能力。C端的B链有丝氨酸蛋白酶功能区,为uPA的活性中心。uPA的合成与分泌受诸多因素影响,如原癌基因V-Src、Ras、细胞因子TNF、INF、IL-1、TGF-β、IGF-1、FGF、基质金属蛋白酶等。一般说来,uPA主要在生理、病理条件下与细胞分化、迁移、组织重建、细胞周围基质降解有关。
尿激酶型纤溶酶原激活物(Urokinase type Plasminogen Activator (uPA) ),蛋白
货号 |
品名 |
包装 |
价格 |
品牌 |
ADG108 |
Urokinase-Receptor (uPAR), human, rec |
200 µg |
9725 |
American Diagnostica Inc |
107 |
urokinase, human, single-chain (scuPA), frozen solution, dry-ice shipment |
25 µg |
6900 |
American Diagnostica Inc |
ADG146NL |
urokinase, human, amino terminal fragment (uPA-ATF), frozen solution, dry-ice shipment |
1 mg |
86375 |
American Diagnostica Inc |
ADG146N |
urokinase, human, amino terminal fragment (uPA-ATF), frozen solution, dry-ice shipment |
0.1 mg |
15500 |
American Diagnostica Inc |
EZ005C |
Urokinase type Plasminogen Activator (uPA) |
1 x 100,000 units |
4710 |
hyphen biomed |
EZ005B |
Urokinase type Plasminogen Activator (uPA) |
1 x 10,000 units |
1035 |
hyphen biomed |
EZ00 |
Urokinase type Plasminogen Activator (uPA) |
1 x 1,000 units |
465 |
hyphen biomed |
ADG125N |
Urokinase (uPA), human, recombinant, LMW, frozen solution, dry-ice shipment |
100 µg |
9725 |
American Diagnostica Inc |
ADG102 |
Urokinase (uPA), human, HMW |
250,000 IU |
询价 |
American Diagnostica Inc |
ADG100 |
Urokinase (uPA), human, HMW |
10,000 IU |
5000 |
American Diagnostica Inc |
128 |
urokinase (uPA), human, HMW |
100,000 IU |
13452 |
American Diagnostica Inc |
ADG244FN |
SPECTROFLUOR® uPA |
10 µmole |
1850 |
American Diagnostica Inc |
尿激酶型纤溶酶原激活物(Urokinase type Plasminogen Activator (uPA) )抗体
货号 |
品名 |
包装 |
价格 |
品牌 |
11651-05021 |
Urokinase (uPA), anti-human |
150 ug |
2800 |
AssayPro |
11651-05011 |
Urokinase (uPA), anti-human |
150 ug |
2320 |
AssayPro |
12172-05021 |
uPA, anti-rat |
150 ug |
2800 |
AssayPro |
12172-05011 |
uPA, anti-rat |
150 ug |
2320 |
AssayPro |
TC42000 |
u-PA purified protein, lyo. 125 µg |
RUO |
3941.28 |
Technoclone |
TC31014 |
Polyclonal anti u-PA antibody (rabbit)1 mg |
RUO |
2650.98 |
Technoclone |
TC31015 |
Polyclonal anti u-PA antibody (rabbit) 5 mg |
RUO |
4128.96 |
Technoclone |
ADG3471 |
murine MAb against uPA-ATF (aa 17-34) |
250 µg |
3950 |
American Diagnostica Inc |
ADG3689 |
murine MAb against uPA b-chain, affinity purified |
250 µg |
4475 |
American Diagnostica Inc |
TC21063 |
Monoclonal anti u-PA antibody 4UK |
RUO |
4715.46 |
Technoclone |
12171-05021 |
ATF-uPA, anti-mouse |
150 ug |
2800 |
AssayPro |
12171-05011 |
ATF-uPA, anti-mouse |
150 ug |
2320 |
AssayPro |
11661-05021 |
ATF uPA, anti-human |
150 ug |
2800 |
AssayPro |
11661-05011 |
ATF uPA, anti-human |
150 ug |
2320 |
AssayPro |
尿激酶型纤溶酶原激活物(Urokinase type Plasminogen Activator (uPA) )试剂盒
货号 |
品名 |
包装 |
价格 |
品牌 |
RK018A |
ZYMUTEST uPA-PAI-1 complexes |
Kit of 96 tests |
7800 |
hyphen biomed |
RK013A |
ZYMUTEST uPA Antigen |
Kit of 96 tests |
7290 |
hyphen biomed |
TC12010 |
u-PA ELISA Kit 96 T. |
RUO |
9196.32 |
Technoclone |
TC16010 |
u-PA Combi Actibind ELISA Kit 96 T. |
RUO |
10603.92 |
Technoclone |
894 |
IMUBIND® uPA ELISA |
96 microwell plate |
10704 |
American Diagnostica Inc |
EU1001-1 |
Human Urokinase (uPA) ELISA Kit |
96 well plate |
4760 |
AssayPro |
CU1001b |
Human Urokinase (uPA) Chromogenic Activity Assay Kit (Indirect Assay) |
96 well plate |
6930 |
AssayPro |
CU1001a |
Human Urokinase (uPA) Chromogenic Activity Assay Kit (Direct Assay) |
96 well plate |
5530 |
AssayPro |
899 |
FEMLE™ uPA/PAI-1 ELISA, – CE |
2×96 microwell plates |
询价 |
American Diagnostica Inc |