上海金畔生物科技有限公司代理New England Biolabs（NEB）酶试剂全线产品，欢迎访问官网了解更多产品信息和订购。
T7 Endonuclease I
EnGen Mutation Detection Kit (NEB #E3321 ) Now Available
- DNA Endonuclease
- Catalyzes the cleavage of DNA mismatches and non-β DNA structures including Holliday junctions and cruciform leaving 3′-OH and 5′-phosphate
- Best at C mismatches and does not recognize all DNA mismatches
- To a lesser extent cleaves across a nick in dsDNA
- Key enzyme for use in genome editing mutation detection workflows
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Endonuclease III (Nth) |NEB酶试剂 New England Biolabs
上海金畔生物科技有限公司代理New England Biolabs（NEB）酶试剂全线产品，欢迎访问官网了解更多产品信息和订购。
Endonuclease III (Nth)
- Bifunctional DNA glycosylase with DNA N-glycosylase and AP lyase activities
- The N-glycosylase activity releases damaged pyrimidines, including thymine glycol and 5, 6-dihydroxythymine, generating an AP site. The AP lyase activity cleaves an AP site via β-elimination, creating a 1-nucleotide gap with 3′-α, β-unsaturated aldehyde and 5′-phosphate termini
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Endonuclease IV |NEB酶试剂 New England Biolabs
上海金畔生物科技有限公司代理New England Biolabs（NEB）酶试剂全线产品，欢迎访问官网了解更多产品信息和订购。
Endonuclease IV
- DNA AP endonuclease
- Catalyzes the cleavage of DNA phosphodiester backbone at AP sites via hydrolysis leaving a 1 nucleotide gap with 3′-hydroxyl and 5′ deoxyribose phosphate (dRP) termini
- Also has 3′-diesterase activity which can remove 3′ phosphate, 3′-α, β-unsaturated aldehyde, phosphoglycoaldehyde, and other 3′ blocking groups
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Endonuclease V |NEB酶试剂 New England Biolabs
上海金畔生物科技有限公司代理New England Biolabs（NEB）酶试剂全线产品，欢迎访问官网了解更多产品信息和订购。
Endonuclease V
The large size of this product has been discontinued.
- DNA endonuclease
- Catalyzes the cleavage of the second DNA phosphodiester backbone 3′ to deoxyinosine, leaving a 3′-OH and 5′ – phosphate
- Endonuclease V activity, to a lesser extent, is also reported on AP site, urea, mismatches, hairpins, loops, and pseudo-Y structures
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Mismatch Endonuclease I |NEB酶试剂 New England Biolabs
上海金畔生物科技有限公司代理New England Biolabs（NEB）酶试剂全线产品，欢迎访问官网了解更多产品信息和订购。
Mismatch Endonuclease I
- DNA Endonuclease
- Catalyzes the cleavage of some DNA mismatches (T:T, G:G and G:T)
- Cleaves the 3rd phosphodiester bond on the 5′ side of the mismatched base in both strands leaving a 5 bp overhang with a 3′- OH and 5′- phosphate
- Best at T mismatches; does not recognize all DNA mismatches
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