标签归档：factor

人类凝血因子Xa Human Factor Xa（HFXa 1011）说明书

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 Enzyme Research ，Enzyme Research 介绍,Enzyme Research 代理,Enzyme Research 代理,Enzyme Research *代理,Enzyme Research 中国代理

Enzyme Research 是一家拥有超过25年的酶研究的实验室，生产和开发多种用于基本凝血研究的多种酶和辅因子。在过去的十年Enzyme Research Laboratories为科学家参与止血和血栓形成的研究提供了宝贵支持。Enzyme Research通过不断追求产品的zui高品质，赢得了世界各地凝血研究实验室的信任。

Human Factor Xa

 

HFXa 1011             Human Factor Xa

Human Factor Xa is prepared from Human Factor X by activation with Russell’s Viper Venom. This RVV-X is removed after activation. Complete activation is observed by SDS-PAGE. Factor Xa along with cofactor Va, phospholipids and calcium ions, （the prothrombinase complex） catalyzes the rapid conversion of prothrombin to thrombin.

Buffer composition = 20 mM Bis Tris/0.7 M NaCl/pH 6.0
*Extinction Coefficient （1%） =11.6
One unit = 8 µg
Molecular Weight = 46,000 daltons

Also available: Human Factor Xaβ, des-Gla Xaβ and 
Xa inactivated

人类凝血因子（Human Factor IXa β）HFIXa 1080说明书

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 Enzyme Research 是一家拥有超过25年的酶研究的实验室，生产和开发多种用于基本凝血研究的多种酶和辅因子。在过去的十年Enzyme Research Laboratories为科学家参与止血和血栓形成的研究提供了宝贵支持。Enzyme Research通过不断追求产品的zui高品质，赢得了世界各地凝血研究实验室的信任。

Human Factor IXa β

 

HFIXa 1080             Human Factor IXa β

Prepared from Human Factor IX by activation with Bovine Factor XIa. This Bovine Factor XIa is removed after activation. Complete activation is observed by SDS-PAGE. The Factor XIa activates Factor IX in a two-step reaction. In the first step, an internal Arg-Ala bond is cleaved, and in the second step, an Arg-Val bond is cleaved. The second cleavage leads to the liberation of an activation peptide from the NH2-terminal portion of the heavy chain to produce Factor IXaβ.

Buffer composition = 20 mM Tris-HCl/0.1 M NaCl /pH 7.4
*Extinction Coefficient （1%） = 14.3 
One unit =5 µg
Molecular Weight = 45,000 daltons

 

人类凝血因子（Human Factor VIIa） HFVIIa说明书

发表于由

 Enzyme Research 是一家拥有超过25年的酶研究的实验室，生产和开发多种用于基本凝血研究的多种酶和辅因子。在过去的十年Enzyme Research Laboratories为科学家参与止血和血栓形成的研究提供了宝贵支持。Enzyme Research通过不断追求产品的zui高品质，赢得了世界各地凝血研究实验室的信任。

Human Factor VIIa

 

HFVIIa             Human Factor VIIa

Prepared from purified Human Factor VII using Human Factor XIIa. The Factor Xlla is removed using affinity chromatography. Purity is determined by SDS-PAGE. Human Factor VIIa reduces to 29,500 and 23,500 with the addition of 2-mercaptoethanol. Activity is determined via clotting assay.  Factor Vlla, in the presence of calcium ions and Tissue factor, activates Factors IX and X to their enzymatically active forms, Factor IXa and Xa.

Buffer composition = 20 mM Tris-HCl/0.1 M NaCl/pH 7.4
*Extinction Coefficient （1%） = 13.9
Molecular Weight = 50,000 daltons

Also available: des-Gla-Human Factor VIIa and 
Factor VIIa inactivated

人凝血因子Human Factor XII （HFXII 1212）说明书

发表于由

 Enzyme Research ，Enzyme Research 介绍,Enzyme Research 代理,Enzyme Research 代理,Enzyme Research *代理,Enzyme Research 中国代理

Enzyme Research 是一家拥有超过25年的酶研究的实验室，生产和开发多种用于基本凝血研究的多种酶和辅因子。在过去的十年Enzyme Research Laboratories为科学家参与止血和血栓形成的研究提供了宝贵支持。Enzyme Research通过不断追求产品的zui高品质，赢得了世界各地凝血研究实验室的信任。
Enzyme Research Laboratories为生物技术公司,制药行业、医院和大学的研究实验室提供用于的纯化抗凝因子。除了其制造能力，Enzyme Research Laboratories也创新研发领域中的血液凝固技术。

Human Factor XII

 

HFXII 1212         Human Factor XII （Hageman Factor）

Purified from fresh frozen human plasma. Human Factor XII is part of the contact activation system. Human Factor XII is a single chain glycoprotein with a molecular weight of about 80,000. Once activated, principally from the action of kallikrein, Factor XII is converted into an active serine protease （Factor α-Xlla） that functions in the in vivo initiation of blood coagulation, fibrinolysis, and kinin formation. Human Factor XII has been purified by ion exchange chromatography. Protein purity is determined by SDS-PAGE and activity is determined via clotting assay.

Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3 
*Extinction Coefficient （1%） =14.1
Molecular Weight = 80,000 daltons

人凝血因子（Human Factor XIII）HFXIII 1313说明书

发表于由

 Enzyme Research ，Enzyme Research 介绍,Enzyme Research 代理,Enzyme Research 代理,Enzyme Research *代理,Enzyme Research 中国代理

Enzyme Research 是一家拥有超过25年的酶研究的实验室，生产和开发多种用于基本凝血研究的多种酶和辅因子。在过去的十年Enzyme Research Laboratories为科学家参与止血和血栓形成的研究提供了宝贵支持。Enzyme Research通过不断追求产品的zui高品质，赢得了世界各地凝血研究实验室的信任。

 

Human Factor XIII

 

HFXIII 1313         Human Factor XIII （Fibrin Stabilizing Factor）

Human Factor XIII is a tetramer composed of two pairs of chains held together by noncovalent bonds. After activation of the zymogen via Thrombin to its active enzyme form, Factor XIIIa is responsible for catalyzing the formation of covalent bridges between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is very insoluble and resistant to lysis.

Buffer composition =50 mM Tris-HCl/0.1 M NaCl/1 mM EDTA/10u/mL aprotinin/20% glycerol/pH 7.5
*Extinction Coefficient （1%）=13.8
Molecular Weight = 320,000 daltons