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Human Heparin CoFactor
HCII Human Heparin Cofactor (HCII)
Prepared from fresh frozen human plasma. Heparin Cofactor II is a single chain glycoprotein with a MW of 65,600 daltons. HCII is a specific inhibitor of thrombin with increased activity in the presence of heparin. Heparin Cofactor II purity is determined by SDS-PAGE and the activity is measured by the ability to inhibit thrombin in the presence of saturating concentrations of heparin.
Buffer =20 mM Tris-HCl/0.15 M NaCl/pH 7.3, containing 0.02% NaN3 (w/v)
*Extinction Coefficient (1%) = 9.1
Molecular Weight = 65,600 daltons