标签归档：hts

JBScreen Kinase 1 – 4 CS-135 JBScreen Kinase HTS CS-204L

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JBScreen Kinase 1 – 4 CS-135 JBScreen Kinase HTS CS-204L

Jena Bioscience在结构学研究方面全面提供晶体筛选试剂盒、优化试剂、工具和各类耗材

JBScreen Kinase 1 CS-131

JBScreen Kinase 2 CS-132

JBScreen Kinase 3 CS-133

JBScreen Kinase 4 CS-134

JBScreen Kinase 1 – 4 CS-135

JBScreen Kinase HTS CS-204L


JBScreen Kinase is a highly specialized screen formulated for the determination of initial crystallization conditions of protein kinases.
Through the use of advanced data mining, crystallization conditions of kinases have been identified from published structures. Data evaluation and verification resulted in the formulation of 96 unique reagents, highly effective for the crystallization of kinases.
JBScreen Kinase utilizes a variety of different precipitating agents, i.e. various molecular weight PEGs, MPD and Ammonium Sulfate, in combination with buffers covering a pH range from 3,1 – 10,0 and numerous additives.

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JBScreen Membrane 1 – 4 CS-309 JBScreen Membrane HTS CS-310

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JBScreen Membrane 1 – 4 CS-309 JBScreen Membrane HTS CS-310

Jena Bioscience在结构学研究方面全面提供晶体筛选试剂盒、优化试剂、工具和各类耗材

JBScreen Membrane 1 CS-301L

JBScreen Membrane 2 CS-302L

JBScreen Membrane 3 CS-303L

JBScreen Membrane 4 CS-304L

JBScreen Membrane 1 – 4 CS-309

JBScreen Membrane HTS CS-310


JBScreen Membrane covers 96 of the most successful conditions for crystallization of membrane proteins. Each individual composition results from an extensive analysis of the crystallization conditions that have yielded membrane protein structures so far.

The JBScreen Membrane crystallization conditions are primarily ordered by type and concentration of the precipitant. This allows easy extraction of all relevant information for a straightforward refinement: Once you get a hit, you immediately see the effects of the neighbouring conditions. The subsequent fine tuning of preliminary hits will be much more efficient.

JBScreen Detergents perfectly complement JBScreen Membrane: This combination enables you to screen a broad range of detergents, while concentrating on the most successful crystallization conditions, making crystallization screening of membrane proteins much more efficient and less time consuming.

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JBScreen Basic 1 – 4 CS-125 JBScreen Basic HTS CS-203L

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JBScreen Basic 1 – 4 CS-125 JBScreen Basic HTS CS-203L

Jena Bioscience在结构学研究方面全面提供晶体筛选试剂盒、优化试剂、工具和各类耗材

JBScreen Basic 1 CS-121

JBScreen Basic 2 CS-122

JBScreen Basic 3 CS-123

JBScreen Basic 4 CS-124

JBScreen Basic 1 – 4 CS-125

JBScreen Basic HTS CS-203L


Despite intensive research, the crystallization of biological macromolecules remains a process of trial and error. Nucleation and crystal growth are influenced by the interaction of many variables, such as temperature, pH, precipitant and salt concentration.
Testing all possible combinations would be too time consuming and would require enormous amounts of sample. One approach to find suitable crystallization conditions is the sparse-matrix method. This method involves screening with an intentional bias towards conditions which have been proven successful in the crystallization of biological macromolecules.

In 1991, Jancarik and Kim published 50 conditions, which were derived from previously crystallized proteins [1]. These and other conditions form the basis of the JBScreen Basic system [1,2]. However, JBScreen Basic is designed to fit the 24-well plate format and like in all other JBScreen crystallization kits, we abstained from the use of cacodylate buffers and replaced them with MES. JBScreen Basic contains 96 unique reagent mixtures for screening a wide range of pH and various salts and precipitants.


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Jena Bioscience JBScreen Classic JBScreen Classic HTS

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Jena Bioscience JBScreen Classic JBScreen Classic HTS

Jena Bioscience在结构学研究方面全面提供晶体筛选试剂盒、优化试剂、工具和各类耗材


JBScreen Classic 1 CS-101L

JBScreen Classic 2 CS-102L

JBScreen Classic 3 CS-103L

JBScreen Classic 4 CS-104L

JBScreen Classic 5 CS-105L

JBScreen Classic 6 CS-106L

JBScreen Classic 7 CS-107

JBScreen Classic 8 CS-108L

JBScreen Classic 9 CS-109L

JBScreen Classic 10 CS-110L

JBScreen Classic 1 – 5 CS-112L

JBScreen Classic 6 – 10 CS-113L

JBScreen Classic 1 – 10 CS-114L

JBScreen Classic HTS I CS-201L

JBScreen Classic HTS II CS-202L

Jena Bioscience JBScreen Classic JBScreen Classic HTS

JBScreen Classic is a crystallization kit designed for efficient and flexible screening of crystallization conditions for proteins, peptides, nucleic acids, macromolecular complexes and water-soluble small molecules.

The JBScreen Classic Kits 1-10 cover 240 of the most prominent buffers for protein crystallization. Their compositions result from data mining of several thousands of crystallized proteins. JBScreen Classic represents the statistically most successful buffers that yielded protein crystals suitable for X-ray diffraction.

The JBScreen Classic buffers are principally ordered by type and concentration of the precipitant. This allows easy extraction of all relevant information and is already a first step to a refinement: Once you get a hit, you immediately see the effects of the neighbouring conditions. Subsequent fine tuning of preliminary hits will be much more efficient.

JBScreen Classic comprises 10 kits of 24 unique reagents in the standard 10 ml bulk format.

JBScreen Classic HTS I+II contains the formulations of the JBScreen system, adopted to fit the 96-well format for high throughput crystallization applications. Each JBScreen Classic HTS deep-well block is pre-filled with 96 sterile conditions at 1.7 ml each.












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