Caspase 8显色底物 (Ac-IETD-pNA)

上海金畔生物科技有限公司提供Caspase 8显色底物 (Ac-IETD-pNA) ,欢迎访问官网了解更多产品信息。

产品编号 C07-01004
英文名称 Ac-IETD-pNA
中文名称 Caspase 8显色底物 (Ac-IETD-pNA)
别    名 N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide; Caspase-8 Substrate; N-Acetyl-Ile-Glu-Thr-Asp-pNA; Caspase-8 Substrate(Chromogenic); N-Acetyl-Ile-Glu-Thr-Asp-pNA; Caspase Substrate, chromogenic;   Ac-IETD-pNA (Caspase 8显色底物); Caspase 8显色底物,Ac-IETD-pNA;
保存条件 Store at -20 °C for one year.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Chromogenic substrate for caspase 8 and granzyme B.
IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.

纯度:>95%(HPLC)
分子式:C34H37N9O11
分子量:747.7
序列:N-Acetyl-Ile-Glu-Thr-Asp-p-Nitroanilide
来源:合成
外观/性状:Lyophilized Yellow Powder
溶解性:Soluble in DMSO
敏感性:对光敏感
简介:Ac-IETD-pNA是Caspase 8的底物,被剪切后可产生黄色的pNA (p-nitroaniline),pNA在405nm附近有强吸收,可以通过测定吸光度来检测Caspase 8的活性。
用途:Chromogenic substrate for caspase-1, -4 and -5. Most potent for caspase-1. ; max of pNA 400nm.
配方:20mM in DMSO: 5mg加入0.39ml DMSO,或每12.77mg加入1ml DMSO,配制成20mM溶液。