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Human Factor IXa β

HFIXa 1080             Human Factor IXa β

Prepared from Human Factor IX by activation with Bovine Factor XIa. This Bovine Factor XIa is removed after activation. Complete activation is observed by SDS-PAGE. The Factor XIa activates Factor IX in a two-step reaction. In the first step, an internal Arg-Ala bond is cleaved, and in the second step, an Arg-Val bond is cleaved. The second cleavage leads to the liberation of an activation peptide from the NH2-terminal portion of the heavy chain to produce Factor IXaβ.

Buffer composition = 20 mM Tris-HCl/0.1 M NaCl /pH 7.4
*Extinction Coefficient （1%） = 14.3 
One unit =5 µg
Molecular Weight = 45,000 daltons