lifesensors公司介绍


lifesensors公司介绍

简要描述:美国LifeSensors 是一家为药物发现和研究市场提供方法和建立可行性技术方法的生物技术公司。

详细介绍

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公司:www.lifesensors.com

美国LifeSensors 是一家为药物发现和研究市场提供方法和建立可行性技术方法的生物技术公司。该公司为泛素和泛素蛋白酶体通路研究提供创新性的研究工具而占据世界。其原核和真核蛋白表达系统SUMOpro 和SUMOstar 已被世界范围内的学术、政府研究机构和制药、生物技术公司广泛应用。 LifeSensors, Inc., a biotechnology company that discovers and develo

美国LifeSensors 中国代理 产品信息

Life Sensors是一家为药物发现和研究市场提供方法和建立可行性技术方法的生物技术公司。该公司为泛素和泛素蛋白酶体通路研究提供创新性的研究工具而占据世界。其原核和真核蛋白表达系统SUMOpro 和SUMOstar 已被世界范围内的学术、政府研究机构和制药、生物技术公司广泛应用。

部分产品信息如下:

Ubiquitin Affinity Reagents (TUBEs)

LifeSensors has developed TUBETandem Ubiquitin Binding Entity) technology for the detection, characterization and isolation of polyubiquitylated proteins from cells and tissue extracts.  TUBEs have 100 to 1000-fold higher affinity for polyubiquitin chains compared to monomer ubiquitin binding domains (UBDs). TUBEs both stabilize and bind to ubiquitylated proteins, serving as an indispensable tool for ubiquitologists.

Our versatile collection of TUBEs includes reagents for isolation/pulldown polyubiquitin conjugates (Agarose-TUBEs, GST- and His6-TUBEs). For immunohistochemistry, use Fluorescent TUBEs conjugated to either fluorescein or TAMRA. Use Biotin-TUBEs for the detection of polyubiquitylated proteins by ligand blotting (“Far Western”).

New Biotin-K63 TUBE 1 (UM304) displays a high sensitivity and specificity for polyubiquitin chains linked through K63. Biotin-K63 TUBE 1 is more sensitive and cost-effective for the detection of K63-linked polyubiquitylated proteins compared to traditional Western blot using chain-specific antibodies. Use Biotin K63-TUBE 1 for ligand blotting, affinity purification from lysates & biological fluids, and in situ detection.

  • K63-SELECTIVE TUBES
  • TUBES (GST TAGGED)
  • TUBES (HIS6 TAGGED)
  • TUBES (BIOTINYLATED)
  • TUBES (FLUORESCENT)
  • TUBES (AGAROSE)
  • TUBES CONSTRUCT LICENSING
  • ANTI-UBIQUITIN ANTIBODIES
  • IMMUNOASSAYS

 

Ubiquitin Derivatives and Chains

  • UBIQUITIN CHAINS
  • UBIQUITIN LYSINE TO ARGININE MUTANTS
  • UBIQUITIN & UBIQUITIN DERIVATIVES
  • SUMO AND SUMO DERIVATIVES & CHAINS

 

Conjugation Assays

The conjugation of ubiquitin to substrates is a multi-step, multi-enzyme process. LifeSensors is committed to supplying high throughput, facile, and robust assays for measuring the activity of Ub conjugating enzymes. These assays work with a wide range of E3 ligases including members of the three major classes of E3 ligases (simple RING class, SCF RING class, and HECT class).  Our E3LITE Customizable Ubiquitin Ligase Kit, as well as the E2 profiling kit based on it, was developed in collaboration with and licensed from Progenra, Inc. (www.progenra.com).

  • E3LITE CUSTOMIZABLE UBIQUITIN LIGASE KIT
  • E2 PROFILING KIT/PANELS
  • E2 SELECT PROFILING & SELECTION KIT

 

Conjugating Enzymes

Ubiquitin/Ubl conjugating enzymes are responsible for the selective modification of substrates. LifeSensors supplies a wide assortment of these enzymes to aid researchers in their efforts to understand the specificity and selectivity of this complex enzyme pathway.

  • E1 ENZYMES
  • E2 ENZYMES
  • E3 ENZYMES

 

Isopeptidases – Assays

Ub/Ubl isopeptidases play key regulatory roles in a variety of disease states including cancer, diabetes, and infectious disease. As such, they represent an attractive class of novel targets for therapeutic development. Approximay 100 Ub/Ubl isopeptidases have been identified in the human genome, however relatively few have been fully characterized. LifeSensors’ offers a wide range of HTS amenable assays substrates for characterizing these proteases and discovering modulators of their activity.

  • CHOP REPORTER SYSTEM
  • CHOP2 REPORTER SYSTEM
  • DIUBIQUITIN IQF SUBSTRATES
  • UBIQUITIN AND MUTANT UBS
  • UBIQUITIN CHAINS
  • UB/UBL AMC
  • UB/UBL RHODAMINE
  • UB/UBL-AMINOLUCIFERINS

 

Isopeptidases – Enzymes

LifeSensors offers the largest collection of deubiquitinating (or deubiquitylating) enzyme (DUB) and Ubl isopeptidases. These enzymes are capable of recognizing and cleaving the isopeptide bond between ubiquitin (or Ubl) moieties or between ubiquitin (or Ubl) and the target protein. Five classes of DUBs exist based on sequence homology. These families include the ubiquitin C-terminal hydrolases (UCH), the ubiquitin-specific processing proteases (USPs), the Machado-Joseph Disease domain proteases, the Otubain proteases (Otu), and JAMM domain proteases. LifeSensors DUBs and Ubl isopeptidases can be utilized for HTS, determining Ub/Ubl specificity or Ub chain linkage type, as well as target substrate specificity.

  • USP FAMILY OF DUBS
  • UCH FAMILY OF DUBS
  • OTU FAMILY OF DUBS
  • JAMM FAMILY OF DUBS
  • MJD FAMILY OF DUBS
  • VIRAL-BACTERIAL DUBS
  • DENEDDYLASES
  • DESUMOYLASES

 

Isopeptidases – Substrates

Deubiquitinating enzymes (DUBs) and UBL isopeptidases recognize and cleave the isopeptide bond between ubiquitin (or UBL) moieties or between ubiquitin (or UBL) and the conjugate protein. Measurement of the activity of these enzymes for kinetic study or inhibitor screening has been traditionally carried out using ubiquitin (or UBL) conjugated to fluorescent leaving groups (AMC or rhodamine) at the C-terminus. While these are suitable substrates for many deubiquitinating enzymes, the cleavage of the amide bond serves as a proxy for the true activity of isopeptidases: cleavage of an isopeptide bond. LifeSensors has recently produced internally-quenched fluorescent diubiquitins, which consist of two ubiquitins singly labeled with a fluorophore and a fluorescent quencher. The cleavage and separation of the isopeptide bond between the labeled ubiquitins results in a fluorescent signal. The IQF-diubiquitins therefore provide sensitive fluorescent substrates for continuous measurement of the isopeptidase activity of DUBs. Lifesensors currently offers IQF-diubiquitin substrates linked through K11, K48 and K63.

  • DIUBIQUITIN IQF SUBSTRATES
  • UBIQUITIN AND MUTANT UBS
  • UBIQUITIN CHAINS
  • UB/UBL AMC
  • UB/UBL RHODAMINE
  • UB/UBL-AMINOLUCIFERINS
  • FLUORESCENCE POLARIZATION SUBSTRATES
  • UBIQUITINATED PEPTIDES

 

Ubiquitin/Ubl Pathway Inhibitors

Increasingly, associations are being made between the ubiquitin system and many human diseases including cancer, neurodegeneration, metabolic disorders and viral infections. Proteolysis mediated by the ubiquitin-proteasome system is regulated by different enzymes, which recently became an attractive target for drug discoveries. LifeSensors offers a number of inhibitors enabling researchers to decipher the function of Ub/Ubl isopeptidases and conjugating enzymes. Along with classical inhibitors of Ub/Ubl isopeptidases such as Ub-vinyl methyl ester and –aldehyde, LifeSensors has a number of small molecule inhibitors. Our new addition includes inhibitors of Ub/Ubl conjugating enzymes. With an evergrowing interest in proteasomal activity that has been linked to cancer, inflammatory and autoimmune diseases, we now offer a collection of proteasome inhibitors. Several inhibitors including bortezomib are already used in the treatment of multiple myeloma. The most commonly used laboratory inhibitors, lactacystin and MG132 are now available in different quantities.

  • UB/UBL VME DERIVATIVES
  • UB/UBL ALDEHYDE DERIVATIVES
  • PROTEASOME INHIBITORS
  • DUB INHIBITORS
  • CONJUGATING ENZYME INHIBITORS
  • P97 INHIBITORS

 

Ubiquitin/Ubl Pathway Antibodies

Antibodies can be used in a wide range of applications including Western blotting, ELISA assays, immunofluorescence and immunoprecipitation. LifeSensors offers quality antibodies recognizing many of the enzymes involved in protein ubiquitylation to aid researchers in their quest to uncover novel protein functions.

  • AMSH Antibody
  • Anti-hSUMO3
  • Anti-SENP1core
  • Anti-SUMO/SUMOstar Antibody
  • Ataxin3 Antibody
  • Ataxin3-Like antibody
  • Den1 Antibody
  • FK2 Ubiquitin Mouse Monoclonal Antibody
  • JosD1 Antibody
  • JosD2 Antibody
  • Otub1 Antibody
  • Otub2 Antibody
  • PLP2 Antibody
  • PLPro Antibody
  • SENP2 Antibody
  • SENP6core Antibody
  • Ssel Antibody
  • UCH-L1 Antibody
  • UCH-L3 Antibody
  • UCH-L5 Antibody
  • USP14 Antibody
  • USP15 Antibody
  • USP2core Antibody
  • USP34core Antibody
  • USP4 Antibody
  • USP5 Antibody
  • USP8 Antibody
  • VU-1 Ubiquitin Mouse Monoclonal Antibody

 

Ubiquitin ELISA

The UbiQuant™ ELISA is a sandwich assay in which total ubiquitin is captured in the wells of a precoated microtiter plate using a proprietary ubiquitin binding reagent.  Unbound protein is removed by washing and then an anti-ubiquitin monoclonal antibody (VU-2) is added.  After removing unbound VU-2, bound antibody is measured using an enzyme linked anti-mouse antibody.

‘UbiQuant ELISA is a great tool to determine the degree of specific protein ubiquitination and total ubiquitin levels in various cell fractions under different experimental conditions”.

Jayakumar Arumugam, Ph.D. University of Texas, M.D. Anderson Cancer Center

  • UBIQUANT QUANTITATIVE UBIQUITIN ELISA
 

 

Ubiquitin Protein Microarray Services

Identification and characterization of the specificity of the substrate-enzyme interactions within the ubiquitylation and deubiquitylation pathways is a current challenge facing the field as a whole and for the individual researcher focused on an individual substrate or enzyme.

Combining unique protein microarray expertise and the most innovative catalog of ubiquitin research tools, LifeSensors’ Ubiquitin Protein Microarray Services provide a powerful microarray platform and straightforward approach to answering many questions at the forefront of ubiquitin research. Services include:

  • E3 ID™ – Determine E3 ligases that ubiquitylate your substrate
  • E3 Substrate ID™ – Identify substrates for your E3 ligase
  • DUB ID™ – Determine DUBs that deubiquitylate your substrate
  • DUB Substrate ID™ – Identify substrates for your DUB
  • Custom Array Services  – Custom services can be developed for any question the arrays can answer

  • UBIQUITIN PROTEIN MICROARRAY SERVICES
 

 

SilenciX Ubiquitin Pathway Knockdown Cell Lines

The first generation of RNAi tools, siRNA and basic plasmids expressing shRNA, reveal certain limitations and off-target effects. Furthermore, successful RNAi experiments currently involve significant optimization requiring additional resources.

SilenciX® stable knockdown cell lines have been developed based on a unique siRNA delivery system developed by tebu-bio Laboratories* providing improved efficacy and stability of RNAi knockdown. Based on EBV-replication, this loss-of-function model ensures chromosome-like replication of the expression vector in a limited and constant number without integration in the genome. This eliminates off-target effects and saturation of the RNAi machinery resulting in specific and homogeneous knockdown of the desired target.

LifeSensors is offering SilenciX®, gene-specific ready-to-use knock-down cell lines ‘silencing’ deubiquitylases (DUBs) and other proteins of interest, including DNA repair-related genes, providing invaluable tools for loss-of-function approaches.

*SilenciX® is a registered trademark of tebu-bio; technology licensed from the CEA.

  • SILENCIX® KNOCK-DOWN CELL LINES –
    DEUBIQUITYLASES (DUBS)
  • SILENCIX® KNOCK-DOWN CELL LINES – DNA
    DAMAGE AND REPAIR
  • SILENCIX® KNOCK-DOWN CUSTOM CELL LINES

 

Custom Ubiquitinated Peptides

Synthesis of custom monoubiquitinated peptides designed from your protein of interest

Choose the protein. . .
Choose the ubiquitination site. . .
We’ll deliver a monoubiquitinated peptide!

LifeSensors can provide custom monubiquitinated peptides from the sequence of your choosing. lsopeptide-linked ubiquitinated peptide reagents are produced using peptide synthesis technologies. Stepwise solid-phase synthesis and fragment condensation / chemical ligation approaches are employed in the synthesis of the ubiquitinated peptides. By utilizing these complementary methodologies for peptide synthesis, a large variety of native and labelled ‘isopeptide-linked’ ubiquitinated peptides can be generated for a variety of applications including:

•    DUB substrates for screening
•    Antigens for generation of site-specific ubiquitin antibodies
•    Structural studies of ubiquitin-binding domain recognition

In contrast to traditional DUB substrates, like ubiquitin-AMC and ubiquitin-rhodamine, which measure cleavage of amide bonds, utilization of a monoubiquitinated peptide as a DUB substrate measures cleavage of an isopeptide bond and allows determination of the influence of sequence proximal to the ubiquitinated lysine on specificity. Profiling activity of a panel of DUBs against a monoubiquitinated histone H2B peptide and a monoubiquitinated PTEN peptide reveals interesting differences in specificity:

  Assessment of DUB activity using monoubiquitinated peptides as a substrates. 2µM monoubiquitinated histone H2B peptide (red), 2µM monoubiquitinated PTEN peptide (blue), and 2µM ubiquitin-rhodamine were incubated with 50nM of each indicated DUB for 30 minutes at 37ºC. Isopeptidase cleavage of ubiquitin from the monoubiquitinated peptides was assessed by LC-MS and is represented as the percent substrate cleaved. Cleavage of ubiquitin-rhodamine was measured as the increase in rhodamine fluorescence at 535nm and is represented as the rate (RFU/sec) relative to USP2c.

Monoubiquitinated PTEN and histone H2B peptides are available from stock.

Length: peptides of almost any length can be synthesized
Quantity: µg to gram quantities
Purity: choose purity levels from 80-98%
Fluorescent modifications: examples include fluorescein, TAMRA, AlexaFluor®, or FRET pairs
Affinity tags: examples include biotin, His6, FLAG®, V5
Ubiquitin options: peptides can be synthesized with wild-type or mutant ubiquitins, including lysine to arginine substitutions or unnatural amino acids

Contact us at info@lifesensors.com or call 610-644-8845 for a quotation or more information.

 

Proteasome Research Tools

The proteasome is a 60 subunit, highly conserved protease complex, representing the products of ~35 genes. It is composed of a 20S core and one or two 19S regulatory particles (26S). Most cellular proteins are marked for degradation by attachment of an ubiquitin chain, which leads to their rapid degradation by the 26S proteasome. The ubiquitin tag binds to the ‘lid’, a 19S particle, followed by disassembly of ubiquitin chains, protein unfolding and subsequent translocation into the 20S proteasome. The 19S proteasome contains 19 different proteins that have the ability to bind, deubiquitinate and unfold polyubiquitinated proteins. Unfolded proteins are further cleaved into short (3-15 amino acids) peptides.

  • 20S PROTEASOME
  • 26S PROTEASOME
  • COP9 (CSN) COMPLEX
  • RPN1 AND RPN2 (26S PROTEASOME REGULATORY
    SUBUNITS) PROTEINS
  • SUC-LEU-LEU-VAL-TYR-AMC (SUC-LLVY-AMC)
  • RPN11 ISOPEPTIDASE SUBSTRATES
  • PROTEASOME INHIBITORS

 

SUMO Research Tools

  • SUMO DECONJUGATING ENZYME SUBSTRATES
  • SUMO CONJUGATING ENZYMES
  • SUMO DECONJUGATING ENZYMES
  • SUMO AND SUMO DERIVATIVES & CHAINS

热烈庆祝成为美国LifeSensors 中国代理

Life Sensors是一家为药物发现和研究市场提供方法和建立可行性技术方法的生物技术公司。该公司为泛素和泛素蛋白酶体通路研究提供创新性的研究工具而占据世界。其原核和真核蛋白表达系统SUMOpro 和SUMOstar 已被世界范围内的学术、政府研究机构和制药、生物技术公司广泛应用。

LifeSensors, Inc., a biotechnology company that discovers and develops enabling technologies for therapeutic, drug discovery and research markets, has established its leadership position by providing innovative research tools for the ubiquitin and ubiquitin-like protein pathways. Its prokaryotic and eukaryotic protein expression platforms SUMOpro and SUMOstar are used worldwide by academic and government institutions, as well as pharmaceutical and biotechnology companies. 
 部分产品信息如下:

PRODUCTS

Expression Systems

Add your protein of interest to the growing bibliography of SUMO-expressed proteins!

Our SUMO-based expression system maximize the yield of soluble, functional proteins in E. coli, yeast, insect and mammalian cells. This system features SUMO functioning as both a chaperonin and as an initiator of protein folding to dramatically improve the solubility and level of expression of your protein of interest. Our desumoylases efficiently and precisely remove SUMO tags, releasing your protein with the desired N-terminal amino acid. Both the SUMO tags and the desumoylases have His6 tags making their subsequent removal fast and easy.

Enhanced Expression and Solubility Using SUMO vs. Other Commonly-used Fusion Tags

 

 

Figure legend. GDF8 (myostatin), a secreted TGFβ family member and difficult-to-express protein, was expressed in E. coli either as a His6, Ub, SUMO, MBP, GST, TRX, or NUS A fusion. Protein fractions were resolved by SDS-PAGE and stained with Coomassie. Arrowheads indicate expected/observed positions of respective protein bands. Of all tags tested, SUMO was the only fusion tag that provided high-level expression of soluble protein.

Express your protein the first time and every time with SUMO. Choose your preferred expression system below and get started with SUMO today!

lifesensors UB101 说明书

世界*实验材料供应商lifesensors正式上海金畔生物为其中国代理,lifesensors 在一直是行业的*,一直为广大科研客户提供zui为的产品和服务,上海金畔生物一直秉承为中国科研客户带来的产品,的服务, 签约lifesensors 就是为了给广大科研客户带来更加完善的产品和服务,您的满意将是我们zui大的收获

lifesensors 中国代理,lifesensors 上海代理,lifesensors北京代理, lifesensors 广东代理,lifesensors 江苏代理 lifesensors 湖北代理, lifesensors 天津, lifesensors 黑龙江代理, lifesensors内蒙古代理, lifesensors 吉林代理, lifesensors 福建代理, lifesensors 江苏代理, lifesensors 浙江代理, lifesensors 四川代理,

 

Life Sensors是一家为药物发现和研究市场提供方法和建立可行性技术方法的生物技术公司。该公司为泛素和泛素蛋白酶体通路研究提供创新性的研究工具而占据世界。其原核和真核蛋白表达系统SUMOpro 和SUMOstar 已被世界范围内的学术、政府研究机构和制药、生物技术公司广泛应用。
 

E1 Activating Enzymes

Ubiquitin Research Tools 
Conjugating Enzymes

E1活化酶

泛素研究工具
共轭酶

泛素E1(UBE1)| 目录号:UB101

UBE1,泛素活化酶,是通过泛素 – 蛋白质异肽键将泛素与靶基质共轭的途径中的*种酶。泛素(G76)的C-末端甘氨酸zui初以ATP依赖的方式腺苷酸化,随后通过转移到UBE1的活性位点半胱氨酸而形成泛素-UBE1硫醇酶来活化。在泛素共轭途径中的其他酶(E2 / E3酶)的帮助下,遍在蛋白质转移到靶基质上的特定赖氨酸。

 

Amount: 50µg
State: Liquid, 50mM Tris (pH8.0), 100mM NaCl, 10% glycerol
MW: 118kDa
Purity: >95% by SDS-Page
Source: Human Recombinant
Fusion Tag: Untagged
Accession Number: NP_695012
Alternate Names: UBA1, POC20, A1S9T, A1ST, AMCX1, GXP1, SMAX2

根据条件,5nM至100nM的典型酶浓度用于体外共轭。

  • 体外泛素链合成和泛素化反应的必需酶
  • 发现E1功能的抑制剂

优点:

使用LifeSensors的E3 Lite Ubiqutin连接酶测定小心地进行活动,以确保可靠的缀合反应。

储存: -80°C,避免冻融循环

 

我们公司zui大优势是强大的采购,

1:基本什么都能进口,血清,抗体,耗材,还有部分限制进口的,

2:货品全,现经营过700多个品牌,基本所有生物试剂耗材都可以进口,特别是冷偏的产品那就更有优势,

3:提供加急服务,一般1-2周到货,超过时限加急费全免

4:价格公道,绝大部分价格有优势,当然不能保证100%产品都是,因为意味着没有服务.

5:良好的信誉,大部分客户我们提供货到付款服务,客户包括清华,北大 交大 复旦,中山等100多所大学,ROCHE,阿斯利康,国药 ,fisher等500多家公司

6:我们还是Santa,Advanced Biotechnologies Inc,lifesensors,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, GePromegaridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,omicronbio, Polysciences,prospecbi, QA-BIO,quickzyme,RESEARCH DIETS,INC,sterlitech;sysy,TriLink BioTechnologies,Inc;worthington-biochem,zyagen等几十家国外公司代理。
7:我们还是invitrogen,qiagen,Midland BioProducts Corporationam,sigma;Promega,roche,merck, rnd,BD, GE,pierce,BioLegend等*批发,欢迎合作。

lifesensors2024年价格表

lifesensors2024年价格表

LifeSensors, Inc. 成立于 1996 年,帮助生命科学家在基础研究、药物发现和诊断方面进行创新。LifeSensors率x推出了用于高质量蛋白表达的SUMO融合系统。泛素蛋白酶体系统 (UPS) 和蛋白质靶向嵌合体 (PROTAC) 的尖d工具的开发正在推动 UPS 领域的发展。聚泛素亲和基质 Tandem Ubiquitin Binding Entities (TUBES) 正在改变科学家在 UPS 中发现和识别神经退行性疾病和药物发现的新型生物标志物的方式。

作为泛素领域的先驱公司,LifeSensors旨在利用其科学领d地位和突破性技术,为生命科学界提供泛素通路的工具和解决方案,这将有助于转化研究和药物开发。

特别告知:为保证产品质量与良好性能,所以在购买相应产品的同时我司会收取一定量的运输费用!!!本次报价有效时间为2024年1月18日—2024年12月14日。

货号 品名 规格 价格 品牌 货期 价格来源
UM-0501M-1000 High Capacity Magnetic Beads TUBE 1 1mL 20064.42  lifesensors 4-6周 上海金畔生物
UM-0411-3000 UbiTest Buffers Only 10pull-downs 2249.10  lifesensors 4-6周 上海金畔生物
PA-0950-0096 PROTAC® Assay Plate 1plate 11126.50  lifesensors 4-6周 上海金畔生物
UM-0411M-1000 UbiTest Magnetic TUBE Elution Kit 10pull-downs 23539.69  lifesensors 4-6周 上海金畔生物
AB-0130-0100 Linear Polyubiquitin Antibody (MAb; clone LUB9) 100ug 12117.60  lifesensors 4-6周 上海金畔生物
SI-0201-5000 Ubiquitin-WT 5mg 749.70  lifesensors 4-6周 上海金畔生物
UM-0402M-1000 TUBE 2 (Magnetic Beads) 1mL 20340.84  lifesensors 4-6周 上海金畔生物
UM-0401-1000 TUBE 1 (Agarose) 1mL 15762.19  lifesensors 4-6周 上海金畔生物
SI-9619-0005 PR-619 5mg 2258.03  lifesensors 4-6周 上海金畔生物
SI-6302-0050 K63-Linked Di-Ubiquitin 50ug 3828.83  lifesensors 4-6周 上海金畔生物
SI-4802-0100 K48-Linked Di-Ubiquitin 100ug 5792.33  lifesensors 4-6周 上海金畔生物
UM-0402-1000 TUBE 2 (Agarose) 1mL 15789.60  lifesensors 4-6周 上海金畔生物
UC-0101-A384 E3LITE Customizable Ubiquitin Ligase Kit 2Plates 23776.20  lifesensors 4-6周 上海金畔生物
UB-0205-0008 Ubc13 0.8nmol 4845.00  lifesensors 4-6周 上海金畔生物
UB-0205-0030 Ubc13 3.0nmol 7229.25  lifesensors 4-6周 上海金畔生物
UB-208H-0030 UBE2R1 (CDC34), His6 3.0nmol 6426.00  lifesensors 4-6周 上海金畔生物
UM-0404M-1000 K63 TUBE (Magnetic Beads) 1mL 20298.00  lifesensors 4-6周 上海金畔生物
UE-0101-0096 UbiQuant™ Kit 1plate 23026.50  lifesensors 4-6周 上海金畔生物
UE-0905-0096 UbiQuant™ Ultra Plate 1plate 8171.90  lifesensors 4-6周 上海金畔生物
UM-0606-0050 M1 TUBE (FLAG) 10pull-downs 10893.60  lifesensors 4-6周 上海金畔生物
DB-0501-0025 USP2core 25ug 2231.25  lifesensors 4-6周 上海金畔生物
UM-0401M-1000 TUBE 1 (Magnetic Beads) 1mL 18961.80  lifesensors 4-6周 上海金畔生物
UM-0411-1000 UbiTest Agarose-TUBE Elution Kit 10pull-downs 18742.50  lifesensors 4-6周 上海金畔生物
SP-4110-0250 SUMOstar Protease 250units 7419.23  lifesensors 4-6周 上海金畔生物
DB-0514-0025 USP10 25ug 6426.00  lifesensors 4-6周 上海金畔生物
DB-0520-0025 USP20 25ug 4908.75  lifesensors 4-6周 上海金畔生物
DB-0599-0025 DUB Cocktail 25ug 11905.95  lifesensors 4-6周 上海金畔生物
DU-0101-4800 K48 PANEL (IQF) 9.2ugofeach 12495.00  lifesensors 4-6周 上海金畔生物
DU-0201-4863 K48/K63 Panel (IQF) 9.2ugofeach 16680.83  lifesensors 4-6周 上海金畔生物
DU-4802-0050 Di-Ubiquitin K48 (IQF, Position-2) 50ug 14994.00  lifesensors 4-6周 上海金畔生物
DU-6303-0050 Di-Ubiquitin K63 (IQF, Position-3) 50ug 14994.00  lifesensors 4-6周 上海金畔生物
PM-7111-0020 pM-SUMOstar Mammalian Intracellular Vector 20ug 8059.28  lifesensors 4-6周 上海金畔生物
PR-1104-0375 NEDD8-CHOP2 Reporter System 30Reactions 20691.72  lifesensors 4-6周 上海金畔生物
PS-0020-0050 20S Proteasome 50ug 3654.79  lifesensors 4-6周 上海金畔生物
PS-0026-0025 26S Proteasome 25ug 3842.21  lifesensors 4-6周 上海金畔生物
PS-0026-0050 26S Proteasome 50ug 6372.45  lifesensors 4-6周 上海金畔生物
SI-0230-0050 Ubiquitin-Rhodamine 50ug 6381.38  lifesensors 4-6周 上海金畔生物
SI-0230-0250 Ubiquitin-Rhodamine 250ug 24646.39  lifesensors 4-6周 上海金畔生物
SI-0250-0050 Ubiquitin-Aldehyde 50ug 2436.53  lifesensors 4-6周 上海金畔生物
SI-0420-0050 hSUMO1-AMC 50ug 6372.45  lifesensors 4-6周 上海金畔生物
SI-6303-0100 K63-Linked Tri-Ubiquitin 100ug 6372.45  lifesensors 4-6周 上海金畔生物
SI-9649-0500 1,10 phenanthroline 50mg 2360.66  lifesensors 4-6周 上海金畔生物
PE-1001-K020 pE-SUMOpro Kan Vector 20ug 8059.28  lifesensors 4-6周 上海金畔生物
PA-0770-P100M PROTAC® In Vitro Ubiquitination Assay Kit – Cereblon, Anti-Mouse 96-wellplateKit 22015.00  lifesensors 4-6周 上海金畔生物
UM-0407M-1000 K48 TUBE HF (Magnetic Beads) 1mL 20298.00  lifesensors 4-6周 上海金畔生物
AB-0101-0250 UCH-L3 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0102-0250 Anti-UCH-L5 Antibody 250ug 6372.45  lifesensors 4-6周 上海金畔生物
AB-0104-0250 Anti-UCH-L1 Antibody 250ug 11714.06  lifesensors 4-6周 上海金畔生物
AB-0120-0500 Anti-Ubiquitin Antibody (MAb; FK2) 500ug 13026.04  lifesensors 4-6周 上海金畔生物
AB-0140-0125 Phospho-Ubiquitin (pS65) Polyclonal Antibody 125ug 7403.29  lifesensors 4-6周 上海金畔生物
AB-0201-0250 Otub1 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0203-0250 Otub2 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0301-0250 Anti-AMSH Antibody 250ug 7778.14  lifesensors 4-6周 上海金畔生物
AB-0401-0250 Anti- Ataxin3 Antibody 250ug 7778.14  lifesensors 4-6周 上海金畔生物
AB-0403-0250 JOSD1 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0404-0250 Anti-JosD2 Antibody 250ug 7403.29  lifesensors 4-6周 上海金畔生物
AB-0501-0250 Anti USP2core Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0504-0250 USP8 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0505-0250 Anti-USP14 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0506-0050 Anti-USP34core Antibody 50ug 1874.25  lifesensors 4-6周 上海金畔生物
AB-0506-0250 Anti-USP34core Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0511-0250 USP4 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0512-0250 Anti-USP5 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0517-0250 Anti-USP15 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0601-0250 AntiSSeL Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0602-0250 PLPro Antibody 250ug 6916.88  lifesensors 4-6周 上海金畔生物
AB-0603-0250 Anti-PLP2 Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0701-0250 Anti-SENP1core Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0702-0250 Anti-ULP1 Antibody 250ug 3467.36  lifesensors 4-6周 上海金畔生物
AB-0703-0250 SENP6core Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0704-0250 Anti-SENP2core Antibody 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-0801-0250 Den1 Antibody (Deneddylase 1) 250ug 5810.18  lifesensors 4-6周 上海金畔生物
AB-7002-0050 Anti-SUMO/SUMOstar Antibody 50ug 5676.30  lifesensors 4-6周 上海金畔生物
AB-7002-0051 HRP-labeled Anti-SUMO/SUMOstar Antibody 50ug 8889.30  lifesensors 4-6周 上海金畔生物
AB-7002-0100 Anti-SUMO/SUMOstar Antibody 100ug 8460.90  lifesensors 4-6周 上海金畔生物
AB-7030-0050 Anti-huSUMO3 Antibody 50ug 8460.90  lifesensors 4-6周 上海金畔生物
AC-1002-0025 3-Methyladenine 25mg 1499.40  lifesensors 4-6周 上海金畔生物
AC-1002-0050 3-Methyladenine 50mg 2623.95  lifesensors 4-6周 上海金畔生物
AC-1002-0100 3-Methyladenine 100mg 3092.51  lifesensors 4-6周 上海金畔生物
AC-1003-0005 Chloroquine diphosphate 5mg 1204.88  lifesensors 4-6周 上海金畔生物
AC-1003-0025 Chloroquine diphosphate 25mg 2142.00  lifesensors 4-6周 上海金畔生物
AC-1003-0050 Chloroquine diphosphate 50mg 3748.50  lifesensors 4-6周 上海金畔生物
AC-1004-0001 E64D 1mg 1311.98  lifesensors 4-6周 上海金畔生物
AC-1004-0005 E64D 5mg 5435.33  lifesensors 4-6周 上海金畔生物
AC-1005-0005 LY-294002 5mg 1874.25  lifesensors 4-6周 上海金畔生物
AC-1005-0025 LY-294002 25mg 6559.88  lifesensors 4-6周 上海金畔生物
AC-1006-0005 Pepstatin A 5mg 843.41  lifesensors 4-6周 上海金畔生物
AC-1006-0025 Pepstatin A 25mg 1874.25  lifesensors 4-6周 上海金畔生物
AC-1007-0005 Vinblastine Sulfate 5mg 1124.55  lifesensors 4-6周 上海金畔生物
AC-1007-0025 Vinblastine Sulfate 25mg 4029.64  lifesensors 4-6周 上海金畔生物
AC-1008-0005 Xanthohumol 5mg 2623.95  lifesensors 4-6周 上海金畔生物
AC-1008-0025 Xanthohumol 25mg 7778.14  lifesensors 4-6周 上海金畔生物
AC-2005-0001 17-AAG 1mg 1124.55  lifesensors 4-6周 上海金畔生物
AC-2005-0005 17-AAG 5mg 2811.38  lifesensors 4-6周 上海金畔生物
AC-2006-0001 17-DMAG HCl 1mg 843.41  lifesensors 4-6周 上海金畔生物
AC-2006-0005 17-DMAG HCl 5mg 3467.36  lifesensors 4-6周 上海金畔生物
AC-2007-0005 Brefeldin A 5mg 1686.83  lifesensors 4-6周 上海金畔生物
AC-2007-0025 Brefeldin A 25mg 5810.18  lifesensors 4-6周 上海金畔生物
AC-2007-0050 Brefeldin A 50mg 9558.68  lifesensors 4-6周 上海金畔生物
CV-1001-0100 SARS-CoV 3CLPro 100ug 16915.00  lifesensors 4-6周 上海金畔生物



关键词:lifesensors、泛素、TUBE技术、SUMO融合系统、蛋白质靶向嵌合体 (PROTAC)