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CpG Methyltransferase (M.SssI)
May be useful for epigenetics – studying cytosine methylation in higher eukaryotes as its specificity mimics the pattern of modification found in their genomes.
- Blocking restriction enzyme cleavage
- Studying of CpG methylation-dependent gene expression
- Probing sequence-specific contacts within the major groove of DNA
- Altering the physical properties of DNA
- Uniform (3H)-labeling of DNA
- Decreasing the number of sites cut by restriction endonucleases, yielding an apparent increase in specificity
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